Results 61 to 70 of about 2,391 (187)
Occurrence and distribution of sarcoptic mange in wild Neotropical canids
Sarcoptic mange affects most Neotropical canid species across multiple countries. It represents a widespread yet largely overlooked conservation threat with potential for cross‐species transmission. Coordinated monitoring and management efforts are needed to understand and mitigate its impacts. Abstract Sarcoptic mange, a contagious skin disease caused
Luan de Jesus Matos de Brito +1 more
wiley +1 more source
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon +21 more
wiley +1 more source
Comparative analysis of walking gaits in South American camelids
Although several studies on the locomotion of Old World camels, mainly the dromedary Camelus dromedarius, exist, detailed data on their relatives, the New World camelids are very scarce. Camelids are distinguished from most mammals by their pacing gaits,
M. Gerken +5 more
core +1 more source
This review evaluates the clinical potential and limitations of intranasal (IN) drug administration in veterinary anaesthesia and emergency care. IN delivery can provide clinically relevant sedation, analgesia and drug reversal, but its success is not universally reliable and is strongly influenced by species‐specific anatomy, formulation ...
Majid Jafarbeglou
wiley +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Twenty new world camelidae primer pairs were selected for cross-species amplification of loci in the old world camelids, the dromedary (Camelus dromedarius) and the bacterian (camelus bactrianus). A panel of DNA samples from 34 unrelated dromedaries (Kenya) and from 34 unrelated bactrians (32 domestic bactrians and two wild bactrians, China) were ...
D.N, Mburu +5 more
openaire +3 more sources
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng +3 more
wiley +1 more source
The South American Camelids: An Expanded and Corrected Edition [PDF]
One of the most significant differences between the New World’s major areas of high culture is that Mesoamerica had no beasts of burden and wool, while the Andes had both.
Bonavia, Duccio
core
Nanobodies: A Promising Toolkit for Diagnostic Applications
This review focuses on camelid‐derived nanobodies (VHHs) and explains how their small size and high stability support robust diagnostic design. Applications across ELISA, lateral flow assays, and PET/SPECT imaging are summarized, along with clinical progress such as caplacizumab.
Wei Wu +11 more
wiley +1 more source
Melanocortin 1 receptor (MC1R), the agouti signaling protein (ASIP), and tyrosinase related protein 1 (TYRP1) are among the major regulators of pigmentation in mammals.
Andrew Hillhouse (6591203) +7 more
core +1 more source

