Results 61 to 70 of about 2,496,464 (330)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

L’utilizzo di Scoto (Sent. IV, d. 15, q. 2, art. 2) e di Bartolo (D. 46.3.99) nel Comentario resolutorio de cambios di Martín de Azpilcueta

open access: yesReti Medievali Rivista
L’articolo discute l’utilizzo e l’interpretazione di due fonti medievali nel Comentario resolutorio di Azpilcueta: le citazioni di Scoto (Sent. IV, d. 15, q. 2, art. 2) e quelle del Commento al Digesto di Bartolo da Sassoferrato (D. 46.3.99).
Paolo Evangelisti
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Benchmarking a Commercial (Sub-)THz Focal Plane Array Against a Custom-Built Millimeter-Wave Single-Pixel Camera

open access: yesIEEE Access, 2020
For the first time, the characteristics of an evolving commercial camera technology that can operate at millimeter-wave frequencies has been independently investigated.
Sang-Hee Shin, Stepan Lucyszyn
doaj   +1 more source

Attosecond Streak Camera

open access: yesPhysical Review Letters, 2002
An electron generated by x-ray photoionization can be deflected by a strong laser field. Its energy and angular distribution depends on the phase of the laser field at the time of ionization. This phase dependence can be used to measure the duration and chirp of single sub100-attosecond x-ray pulses.
Itatani, J.   +5 more
openaire   +4 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas   +18 more
wiley   +1 more source

New Monte Carlo Localization Using Deep Initialization: A Three-Dimensional LiDAR and a Camera Fusion Approach

open access: yesIEEE Access, 2020
Fast and accurate global localization of autonomous ground vehicles is often required in indoor environments and GPS-shaded areas. Typically, with regard to global localization problem, the entire environment should be observed for a long time to ...
Hyunggi Jo, Euntai Kim
doaj   +1 more source

Optical approach of a hypercatadioptric system depth of field [PDF]

open access: yes, 2010
A catadioptric system is composed of a mirror and a perspective camera. Since the mirror is curved and the distance between the mirror and the camera is short, some parts of the panoramic image keep blurred.
Zenou, Emmanuel, Zhang, Siyuan
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

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