Results 41 to 50 of about 118,950 (268)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Camera Obscura, Camera Lucida [PDF]

open access: yes, 2003
<div>Annette Michelson's contributions to art and film criticism over the last three decades have been unparalleled. This volume honors her unique legacy with original essays by some of the many scholars who have been influenced by her work. Some continue her efforts to develop theoretical frameworks for understanding modernist art, while others ...
openaire   +2 more sources

Performance enhancement of optical camera communication system using optical camera communication coding and region‐of‐interest detection

open access: yesIET Optoelectronics, 2021
Optical camera communication (OCC) is considered an important transmission scheme in implementing indoor navigation, beacons, and other Internet of Things applications.
Duy Thong Nguyen, Youngil Park
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Density of fishers and the efficacy of relative abundance indices and small‐scale occupancy estimation to detect a population decline on the Hoopa Valley Indian Reservation, California

open access: yesWildlife Society Bulletin, 2011
We used a mark–resight design to calculate density estimates of fisher (Martes pennanti), a candidate for listing under the United States Endangered Species Act, on the Hoopa Valley Indian Reservation in northwestern California, USA in order to determine
Sean M. Matthews   +3 more
doaj   +1 more source

Systems Engineering Baseline Concept of a Multispectral Drone Detection Solution for Airports

open access: yesIEEE Access, 2017
The baseline concept for a multispectral drone detection (MSDD) system for use in airports is generated. The baseline development process is based on a modified system of systems architecting with ilities (SAI) method.
Rick L. Sturdivant, Edwin K. P. Chong
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

A camera in the surgery [PDF]

open access: yesBritish Journal of General Practice, 2013
Photography has been used extensively in medicine since the 19th century, and now the universal availability of the digital camera has made the recording of images, archiving, and their transmission over the internet straightforward. When downloaded onto the practice computer, pristine images can, at the touch of a few keys, appear and can be used not ...
Lara, Howells, Nigel, Masters
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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