Results 91 to 100 of about 479,679 (288)

Determinants of Sexual Practices Among Secondary School Students in Nigeria: Focusing on Socio-Cultural and School-Related Factors [PDF]

Rwanda Medical Journal, 2020
BACKGROUND: Very little is known about the school-related and sociocultural determinants of sexual practices amongst Nigerian secondary school students. This study aims to determine such factors amongst them.
K. Kanmodi, O. Fagbule, K. Ogunniyi, M. Ogbeide, V. Samuel, E. Aliemeke, Y. Olatunji, T. Isola, H. Adewuyi, S. Musa   +9 more
doaj  

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

Selling Favors in the Lab: Experiments on Campaign Finance Reform [PDF]

Substantial academic interest and public policy debate centers on campaign finance reform. Campaign resources can provide benefits to constituencies if candidates use them to fund the distribution of useful information.
Daniel Houser, Thomas Stratmann
core  

Mixing‐Driven Defects and Composition Evolution in Multi‐Material Metal Additive Manufacturing

Advanced Science, EarlyView.
Operando synchrotron X‐ray imaging coupled with high‐fidelity multiphysics modeling uncovers how inter‐material mixing reshapes keyhole dynamics and drives distinct pore‐formation pathways in multi‐material laser powder bed fusion (LPBF). Composition‐dependent instabilities trigger defects, whereas rescanning suppresses porosity and homogenizes Cu ...
Zhilang Zhang, Steve Gaudez, Mario Togni, Steven Van Petegem, Markus Bambach, Mamzi Afrasiabi   +5 more
wiley   +1 more source

Monitoring compliance with national smokefree regulations eight months after implementation in Puebla and Aguascalientes, Mexico

Revista Panamericana de Salud Pública
Objective. To assess compliance with smokefree regulations at hospitality venues in two cities 8 months after implementation of national regulations establishing 100% smokefree areas in all indoor workplaces, public places, and public transportation ...
Alejandra Bolaños Casarín, Kai Wasson, Eduardo del Castillo Valadez, Jimena Fernández Guadarrama, Oscar Medina Castro, Brahim Zamora Salazar, Oscar Daniel Amaro Jiménez, Emanuel del Castillo Aguirre, Valentina Ochoa Vivanco, Daniel McGoldrick, Jasmine Keng, Ernesto M. Sebrié   +11 more
doaj   +1 more source

Machine Learning‐Driven Prediction of Microplastic Aging Processes and Environmental Risk Assessment Across Multi‐Media Systems

Advanced Science, EarlyView.
This perspective proposes a cohesive machine learning strategy to decode microplastic aging. It advocates for Federated Learning to dismantle global data silos and introduces the TRACE framework (TRansport, Aging, Corona, Ecotoxicity). By integrating physics‐informed modeling with causal discovery, this approach bridges the laboratory‐field gap to ...
Yaping Lyu, Xinran Qiu, Xing Li, Tianhuan Yang, Xuetao Guo, Hao Qiu, Peng Zhang   +6 more
wiley   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Campaign Finance Laws and Political Efficacy: Evidence From the States [PDF]

The decline of political efficacy and trust in the United States is often linked to the rise of money in politics. Both the courts and reform advocates justify restrictions on campaign donations and spending as necessary for the improvement of links ...
Jeffrey Milyo, David M. Primo
core  

The CLEF campaign [PDF]

, 2001
The Cross-Language Evaluation Forum (CLEF) provides an infrastructure aimed at supporting the development, testing and evaluation systems for cross-language information retrieval, and for monolingual information retrieval of European Languages other than English.
Braschler M, Peters C
openaire   +2 more sources

Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective

Advanced Science, EarlyView.
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok, Jesús Valdés‐Hernández, Varinia Bernales, Alán Aspuru‐Guzik, Alex Zhavoronkov   +4 more
wiley   +1 more source