Results 141 to 150 of about 83,933 (315)

Illuminating exceptional family physicians. [PDF]

Can Fam Physician
Allan M.
europepmc   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

James A. Estes: An ecologist's quest to understand nature. [PDF]

Proc Natl Acad Sci U S A
Hay ME, Williams TM, Power ME.
europepmc   +1 more source

Fishing kits and equipment, by Samuel G. Camp ...

, 1910
Samuel Granger Camp
openalex   +2 more sources

Two Components of a Secreted Cell Number-counting Factor Bind to Cells and Have Opposing Effects on cAMP Signal Transduction in Dictyostelium [PDF]

, 2003
Debra A. Brock, Karen Ehrenman, Robin R. Ammann, Yitai Tang, Richard H. Gomer   +4 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Editorial: Sport and active living: nature challenge vis-à-vis inter-human competition. [PDF]

Front Sports Act Living
Stebbins RA, Gravelle F, Davidson L, Gammon S.   +3 more
europepmc   +1 more source

New Insights into the Roles of cAMP and InsP3 on Odor-Processing and Olfactory-Driven Behaviors

, 2017
Meena Sriti Murmu
openalex   +1 more source

A Simplified Three‐Tailed N‐Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose‐Accumulated mRNA Delivery for Anti‐Obesity Therapy

Advanced Science, EarlyView.
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma, Yunxuan Liu, Huijuan Zhang, Yian Fang, Yizhe Xue, Junsheng Xue, Ziqiong Jiang, Tianyan Zhou, Yanyun Hao, Fei Xie, Lei Miao   +10 more
wiley   +1 more source

Impact of habitat associations on saproxylic beetle assemblages and their damage severity. [PDF]

Sci Rep
Batchudur BA, Tsagaantsooj N, Ganbat D, Boldgiv B.   +3 more
europepmc   +1 more source