Results 51 to 60 of about 11,532,513 (297)

Perspective: the gist of public tender for service design [PDF]

open access: yes, 2018
Governments around the world are increasingly formalising design as an innovative approach to renew public services. In this development, the capabilities of external service design consultancies often play an important part, which calls for new insights
Person, Oscar   +3 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Determinant moments for the design management occurrence in fashion industry [PDF]

open access: yes, 2018
Design management has occupied a privileged place in debates related to the field of design and innovation in fashion industry. The apparel industry, in particular, presents a dynamic character, requiring constant updates on raw materials, changes in ...
Libânio, Cláudia de Souza   +5 more
core   +1 more source

Digital Tools for Collaborative Design Processes [PDF]

open access: yes, 2021
Diverse practices of collaboration in design, research, teaching, or academia increasingly rely on digital online tools to facilitate processes of working and creating together. But a lot of the available digital platforms are not necessarily designed
Ibach, Merle, Greiner-Petter, Moritz
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Architectural design principles of a University Campus that create an educational atmosphere

open access: yesARTEKS : Jurnal Teknik Arsitektur
Architectural design holds a pivotal role in shaping the development of university campuses. This study critically examines the extent to which the architectural plans of four campuses correspond with the conceptual framework of an educational campus ...
Diah Cahyani Permana Sari   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Light-field based 3D optical tweezers [PDF]

open access: yesEPJ Web of Conferences
Optical tweezers are designed to trap nano- and micro-scale particles. Once trapped, it is possible to move the particles but this requires complex mechanical adjustments to the optical system.
Le Priol Etienne   +2 more
doaj   +1 more source

Exploring the State of Knowledge and Gaps Regarding Sustainability within Viennese Construction Industry

open access: yesActa Polytechnica CTU Proceedings, 2022
Different approaches to assess sustainability goals are found in construction sector, mainly related to energy efficiency through building technology and high-tech components, to low-tech strategies based on passive planning methods, the use of renewable
Aída Santana-Sosa   +3 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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