Renal Biopsy: Use of Biomarkers as a Tool for the Diagnosis of Focal Segmental Glomerulosclerosis
Disease Markers, Volume 2014, Issue 1, 2014., 2014 Focal segmental glomerulosclerosis (FSGS) is a glomerulopathy associated with nephrotic syndrome and podocyte injury. FSGS occurs both in children and adults and it is considered the main idiopathic nephrotic syndrome nowadays. It is extremely difficult to establish a morphological diagnosis, since some biopsies lack a considerable quantifiable number ...
Crislaine Aparecida da Silva +9 more
wiley +1 more source
Ribbing disease: a systematic review [PDF]
, 2018 Orthopaedics, Trauma Surgery and ...
Dijkstra, S.P.D. +3 more
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Juvenile Paget’s disease with compound heterozygous mutations in TNFRSF11B presenting with recurrent clavicular fractures and a mild skeletal phenotype [PDF]
, 2020 Juvenile Paget’s disease (JPD) is a rare recessively-inherited bone dysplasia. The great majority of cases described to date have had homozygous mutations in TNFRSF11B, the gene encoding osteoprotegerin.
Ali +32 more
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BioMed Research International, Volume 2014, Issue 1, 2014., 2014 Most researchers agree that idiopathic scoliosis (IS) is a multifactorial disease influenced by complex genetic and environmental factors. The onset of the spinal deformity that determines the natural course of the disease, usually occurs in the juvenile or adolescent period.
Roman Nowak +4 more
wiley +1 more source
Elimination of Pain and Improvement of Exercise Capacity in Camurati-Engelmann Disease With Losartan [PDF]
, 2020 Background: Camurati-Engelmann disease (CED) is a rare disorder, with approximately 250 described cases in the literature.
A A +8 more
core
Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model [PDF]
, 2013 Dysregulated transforming growth factor beta (TGF-β) signaling is associated with a spectrum of osseous defects as seen in Loeys-Dietz syndrome, Marfan syndrome, and Camurati-Engelmann disease.
Azhar, Mohamad +18 more
core +1 more source
Scientifica, Volume 2013, Issue 1, 2013., 2013 Although it has long been recognized that inflammation, a consequence of immune‐driven processes, significantly impacts bone turnover, the degree of centralization of skeletal and immune functions has begun to be dissected only recently. It is now recognized that formation of osteoclasts, the bone resorbing cells of the body, is centered on the key ...
M. Neale Weitzmann +2 more
wiley +1 more source
Functional Role Of Mepe In Tooth Mineralization: Mediation By Tgf-Beta1 [PDF]
, 2015 Transforming growth factor-β1 (TGF-β1) is one of the most abundant cytokines of the dentin-pulp complex that regulates a broad range of biological processes related to matrix synthesis and ultimately tooth formation, including secretion and ...
Gullard, Angela
core +1 more source
СКЛЕРОТИЧЕСКИЕ ОСТЕОДИСПЛАЗИИ (ОБЗОР ЛИТЕРАТУРЫ) [PDF]
, 2016 Sclerotic osteodysplasias represent a group of relatively rare diseases; a common feature of them is the diffuse or local bone sclerosis. The reasons for their development are congenital abnormalities of endochondral and intramembranous bone formation ...
Nekhoroshkova T.V. +2 more
core +2 more sources
Mutations in STAT3 and IL12RB1 impair the development of human IL-17–producing T cells [PDF]
, 2008 The cytokines controlling the development of human interleukin (IL) 17--producing T helper cells in vitro have been difficult to identify. We addressed the question of the development of human IL-17--producing T helper cells in vivo by quantifying the ...
Ludovic de Beaucoudrey +45 more
core +3 more sources