Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni +5 more
wiley +1 more source
Closed‐loop Recycling of Sulfide Solid Electrolytes from Spent Solid‐State Sodium Batteries
Closed‐loop recycling of sulfide solid electrolyte via a mild dissolution–recrystallization–thermal treatment process enables efficient recovery from spent all‐solid‐state sodium batteries. The regenerated material preserves the crystal structure, local coordination, and chemical states, maintaining high ionic conductivity, reduced interfacial ...
Yongtai Xu +14 more
wiley +1 more source
Prevalence and Correlates of Reporting a Gabapentin Prescription for Pain Among People Who Use Opioids: A Longitudinal Community-Recruited Study. [PDF]
Piret EM +7 more
europepmc +1 more source
A new benign solvent (1,3‐diphenylacetone) enables a simple, safe, and sustainable dissolution and gelation method to convert waste PET into low density, monolithic aerogels with high mechanical strength (E = 20 MPa) and remarkably low thermal conductivity (k = 21.9 to 28.9 mW/m·K).
Kira R. Baugh +9 more
wiley +1 more source
Cannabis Legalization Outcomes in Canada: Trading Off Increased Health Problem for Reduced Crime Burdens Is Not Good Enough. [PDF]
Fischer B +4 more
europepmc +1 more source
Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen +19 more
wiley +1 more source
Correction: Test-adjusted estimation for pertussis incidence in greater Toronto, Canada, 1993-2006. [PDF]
Lee CE +4 more
europepmc +1 more source
Hierarchical Structure and Fabrication of Functionally Graded Biointerfaces in the Mussel Byssus
The byssus is a fibrous protein‐based holdfast consisting of mechanically distinct interfaces, which mussels use to anchor their soft living tissue to hard seashore surfaces. Here, multiscale methodologies were used to elucidate the compositional and structural features underlying these functionally graded interfaces and how they are fabricated through
Lucia Youssef +4 more
wiley +1 more source
Multilayered Digital Microfluidic Chip for Cell‐Based Assays
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden +2 more
wiley +1 more source
Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets
This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu +7 more
wiley +1 more source

