Results 171 to 180 of about 1,230,981 (192)

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Cognitive behavioural therapy compared to compensatory strategy training for persisting memory symptoms after concussion in adults: protocol for a randomised controlled trial. [PDF]

BMJ Open
Silverberg ND, Burke MJ, Debert CT, Klotz T, Zemek R, Schmidt J, Panenka WJ, Perez DL, Bayley MT, Tartaglia MC, Srivastava A, Howard A, Mitton C, Rathbone M, Byworth M.   +14 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Implementing single-dose HPV vaccination in Canada. [PDF]

Hum Vaccin Immunother
Leggatt M, Moothathamby N, Dubé È, Shapiro GK.   +3 more
europepmc   +1 more source

Projected Exposure of Canadian Children to Rare, High-Severity Heatwaves Under Continued Warming. [PDF]

Geohealth
Zaerpour M, Taleghanidoozdoozan S, Steele BJ, Hatami S, Xu LL, Papalexiou SM, Helldén D.   +6 more
europepmc   +1 more source

Highly pathogenic avian influenza in Canada: Spatial analysis of ecological hot and cold spots and environmental drivers. [PDF]

One Health
Nia ZM, Bragazzi NL, Gillies M, Gardner E, Kong JD.   +4 more
europepmc   +1 more source