Results 171 to 180 of about 1,159,365 (196)

International disruptions to cancer diagnosis and stage at presentation during the COVID-19 pandemic in 2020: an International Cancer Benchmarking Partnership (ICBP) population-based study.

Lancet Oncol
Morgan E, Bardot A, Langselius O, Rutherford MJ, Elkader HA, Bennett D, Brennan A, Bucher O, Butler J, Cameron DA, Canfell K, Chiam K, Chiarelli A, Creighton N, De P, Evans S, Fitzpatrick D, Guren MG, Hannah J, Huws DW, Jackson CGCA, Kønig SM, Kumar E, Larønningen S, Lawler M, Liu Q, McClure C, Mehmood A, Mitchell H, Morrison DS, Murray D, Norwood T, Phillips KAM, Ransom D, Shack L, Smits S, Saint-Jacques N, Marvelde LT, Tran D, Turner D, Ursin G, Vernon S, Walker MJ, Woods RR, Zhang B, Bray F, Soerjomataram I.   +46 more
europepmc   +1 more source

Increased Experiences of Multiple Forms of Discrimination in Healthcare Settings During the COVID-19 Pandemic Among African, Caribbean, and Black (ACB) People Across Canada: A Cross-Sectional Survey. [PDF]

Healthcare (Basel)
Etowa J, Buh A, Kaida A, Baidoobonso S, Osuji J, Odhiambo JA, Ndongmo L, Etowa E, Ghose B, Este D.   +9 more
europepmc   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

The approaches, theories, models, frameworks, and methods in designing toolkits to support healthcare providers in health behaviour change: A scoping review protocol. [PDF]

PLoS One
Scandiffio J, Sureshkumar A, Feng G, Gaid D, Wasilewski M, Woods N, Donkers S, Simpson R, Munce S.   +8 more
europepmc   +1 more source

Transwell membrane material affects myogenic differentiation in human primary myoblast-adipocyte co-culture. [PDF]

Physiol Rep
Plissonneau C, Tam BT, Garneau PY, Morais JA, Piekny A, Santosa S.   +5 more
europepmc   +1 more source

Appropriateness and determinants of outpatient antibiotic use among migrants in British Columbia, Canada: a population-based study. [PDF]

JAC Antimicrob Resist
Chang CY, Chuang E, Thiruchelvam D, Patrick DM, Saatchi A, Lishman H, Brown K, Langford BJ, Leung V, Daneman N, Silverman M, Ramlackhan K, Schwartz KL, Marra F.   +13 more
europepmc   +1 more source