Results 21 to 30 of about 1,230,981 (192)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
México, Estados Unidos, Canadá, 1993-1994
, 2020 En este segundo volumen bianual de la serie "México-Estados Unidos-Canadá", que publica el Programa de Estudios sobre Estados Unidos y Canadá del Centro de Estudios Internacionales, continuamos con nuestro propósito de presentar un análisis periódico de ...
Vega Cánovas, Gustavo - Compilador/a o Editor/a
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
, 2011 Texto en portugúesVersión en inglés disponible en la Biblioteca Digital del IDRC: Partnerships for knowledge : highlights from phase V (2008-2011) of the Canada-Latin America and the Caribbean Research Exchange Grants (LACREG) programVersión española en ...
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
, 2011 Versión en inglés disponible en la Biblioteca Digital del IDRC: Partnerships for knowledge : highlights from phase V (2008-2011) of the Canada-Latin America and the Caribbean Research Exchange Grants (LACREG) programVersión portugués en la biblioteca ...
core +1 more source
Las relaciones económicas interprovinciales en Canadá [PDF]
, 2005 Agradecimientos; Introducción; Las relaciones económicas interprovinciales; Las raíces históricas de las relaciones económicas interprovinciales en Canadá; El nacimiento de la confederación y el mercado nacional: la Política Nacional de Canadá; Ganadores
Dávalos, Elisa
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FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Programa de mano - InTabvla, música antigua (Colombia / Canadá)
, 2022 "InTabvla fue fundado en 2016 por el laudista Esteban La Rotta y la especialista en instrumentos de tecla antiguos Katelyn Clark, quienes se encontraron gracias a su pasión y afinidad por la música medieval tardía.
InTabvla - Música antigua (Colombia / Canadá)
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