Results 121 to 130 of about 59,343,436 (261)

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

open access: yesAdvanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li   +19 more
wiley   +1 more source

Canal Lock

open access: yes
One black and white photographic slide of a canal lock on a canal, probably the Ohio and Erie Canal in eastern Ohio. Water flows through the struncture and into the foreground while the towpath lines the water on the right.
Canal Society of Ohio
core  

Efectos nutricionales de los polisacáridos no amiláceos en pollo de engorde de la línea Ross

open access: yesCiencia y Agricultura, 2013
Los Polisacáridos no Amiláceos (PNA) son un tipo de carbohidratos presentes en antinutricionales con el fin de disminuir los niveles de grasa corporal. Para esta investigación se contó con tres grupos de pollos de engorde de la línea Ross: al primero se ...
Diana Patricia Alba-Laverde
doaj  

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

open access: yesAdvanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer   +12 more
wiley   +1 more source

Walhonding Canal Triple Locks

open access: yes
One black and white photographic print of the remains of a canal boat sitting in the Walhonding Canal Triple Locks in Roscoe Village in Coshocton County, Ohio. The Walhonding Canal was a small feeder canal for the Ohio and Erie Canal in Coshocton County,
Canal Society of Ohio
core  

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

open access: yesAdvanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne   +15 more
wiley   +1 more source

O impacto da mudança no uso do solo sobre o sequestro de carbono e seus atributos microbiológicos [PDF]

open access: yes, 2008
Dissertaçao (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Ambiental.A alteração no uso da terra pode modificar os estoques de carbono no solo e aumentar as emissões de CO2 para a ...
Primieri, Silmar
core  

SIRT5‐Mediated Desuccinylation of ACAA2 Protects Against Calcium Oxalate‐Induced Kidney Injury by Regulating Fatty Acid Oxidation to Suppress Mitochondrial Oxidative Injury and Ferroptosis

open access: yesAdvanced Science, EarlyView.
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang   +6 more
wiley   +1 more source

Unidentified Canal Lock Remains 5

open access: yes
One black and white photographic slide of an unidentified canal lock on the canal, probably the Ohio and Erie Canal in eastern Ohio. A train sits on a railroad to the right of the canal.
Canal Society of Ohio
core  

SAV1 in Cooperation With FKBP52 Participates in Implantation

open access: yesAdvanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao   +10 more
wiley   +1 more source

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