Results 141 to 150 of about 7,241,930 (347)
Effect of cyclic loading on bond strength of fiber posts to root canal dentin.
Frontiers in Dentistry, 2014 The aim of this study was to evaluate the effect of cyclic loading on the bond strength of quartz fiber posts to root canal dentin after different surface treatments of different regions of root canal dentin.Forty-eight single-rooted human teeth were ...
Zahra Khamverdi +2 more
doaj
TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy
Advanced Science, EarlyView.We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng +9 more
wiley +1 more source
SURFACE SEA WATER CARBON DIOXIDE FLUXES AND CARBON STORAGE OF PRIMARY PRODUCERS IN HYOGO CANAL
, 2023 Sosuke OTANI +4 more
openalex +2 more sources
Advanced Science, EarlyView.This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu +11 more
wiley +1 more source
Advanced Science, EarlyView.Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao +14 more
wiley +1 more source
Surface water quality in a water run-off canal system: A case study in Jubail Industrial City, Kingdom of Saudi Arabia [PDF]
, 2016 Zia Mahmood Siddiqi +2 more
openalex +1 more source
GeoSACS: Geometric Shared Autonomy via Canal Surfaces
8 ...
Rajapakshe, Shalutha +4 more
openaire +2 more sources
Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Advanced Science, EarlyView.Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source
Assessment of Poly (diallyl dimethyl ammonium chloride) and Lime for Surface Water Treatment (Pond, River, and Canal water): Seasonal Variations and Correlation Analyses [PDF]
Shagufta Jabin +4 more
openalex +1 more source