Results 61 to 70 of about 378,690 (301)

Effect of 2D and 3D ECM and Biomechanical Cues on Human iPSC‐Derived Liver Progenitor Cell Differentiation

Advanced Healthcare Materials, EarlyView.
An engineered microtissue model is developed and optimized to investigate human liver development. Extracellular matrix composition and mechanical forces are tuned using high‐throughput assays. Human induced pluripotent stem cells serve as the cellular source, enabling the observation of de novo patterned differentiation.
Ishita Jain, Brock Grenci, Hyeon Ryoo, Yang Yuan, Salman R. Khetani, Gregory H. Underhill   +5 more
wiley   +1 more source

Special canal surfaces with Bishop frame and quaternions [PDF]

Surveys in Mathematics and its Applications
The purpose of this paper is to show that canal and tubular surfaces can be obtained by special curves. Also, we reckon the equations of these surfaces with Bishop frame and acquire some corollaries for special curves.
Abdussamet Çalışkan
doaj  

Characteristics of direct human impacts on the rivers Karun and Dez in lowland south-west Iran and their interactions with earth surface movements [PDF]

, 2015
Two of the primary external factors influencing the variability of major river systems, over river reach scales, are human activities and tectonics.
Frostick, Lynne E., Heyvaert, Vanessa M. A., Heyvaert, Vanessa M.A., Parsons, Daniel R., Walstra, Jan, Woodbridge, Karl, Woodbridge, Kevin P.   +6 more
core   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Induction of Nephron–Ductal Dual Lineages via Early Retinoic Acid Signaling Establishes a Platform for Fully Patterned Kidney Organoids

Advanced Healthcare Materials, EarlyView.
A simplified, co‐culture‐free protocol for kidney organoids that generate segmented nephrons, including collecting ducts, has been developed. Early low‐dose RA with FGF9 induces balanced anterior–posterior IM patterning and dual UE/MM lineage commitment. BMP7 enhances nephron progenitor maturation.
Jung Hwa Lim, Seeun Kim, Dong Hyun Lee, Dae Hun Kim, Hye Bin Lee, Ye Seul Son, Mi‐Young Son, Soo Jin Oh, Ji‐Yoon Lee, Mi‐Ok Lee, Hyun Soo Cho, Dae‐Soo Kim, Cho‐Rok Jung, Hyun Mi Kang   +13 more
wiley   +1 more source

Comparative evaluation of depth of penetration of sealer after using EDTA, citric acid and R-EDTA as last irrigant under confocal laser microscopy

Endodontology
Aim: This original research examines potential of root canal sealers to penetrate the dentin. Movement of root canal sealer into dentinal tubules decreases the residual space for the entombing of bacteria and provides the hermetic seal.
Asit Vats, Arundeep Singh
doaj   +1 more source

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

Advanced Healthcare Materials, EarlyView.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite, Emilie Duthoo, Mathilde Lefevre, Elise Hennebert, Patrick Flammang   +4 more
wiley   +1 more source

Three-Dimensional Analysis of Root Anatomy and Root Canal Curvature in Mandibular Incisors Using Micro-Computed Tomography with Novel Software

Applied Sciences, 2020
Root canal treatment of mandibular incisor is difficult because of the narrow pulp space and apical curvature. The aim of this study was to measure the anatomical indicators of the mandibular incisors in Koreans using micro-computed tomography (MCT) with
JongKi Lee, Shin-Hoon Lee, Jong-Rak Hong, Kee-Yeon Kum, Soram Oh, Adel Saeed Al-Ghamdi, Fawzi Ali Al-Ghamdi, Ayman Omar Mandorah, Ji-Hyun Jang, Seok Woo Chang   +9 more
doaj   +1 more source

Metallofullerenol Sc3N@C80(OH)18: A New Generation Radioprotector Protecting Human Erythrocytes Against Multiple Biochemical Damage Modes Upon Gamma Irradiation, Identifying It as a Scavenger of Short‐ and Long‐Lived Radicals

Advanced Healthcare Materials, EarlyView.
Metallofullerenol Sc3N@C80(OH)18 demonstrates strong radioprotective properties as a scavenger of both short‐ and long‐lived radicals. The study reveals protection of human erythrocytes from γ‐radiation–induced biochemical damage via post‐irradiation removal of primary and secondary reactive oxidants, supported by pulse radiolysis kinetics.
Jacek Grebowski, Maciej Studzian, Szymon Lekki‐Porebski, Anna Konarska, Marian Wolszczak, Grzegorz Litwinienko, Lukasz Pulaski   +6 more
wiley   +1 more source

Clinical applications of custom-made vaginal cylinders constructed using three-dimensional printing technology. [PDF]

, 2016
PurposeThree-dimensional (3D) printing technology allows physicians to rapidly create customized devices for patients. We report our initial clinical experience using this technology to create custom applicators for vaginal brachytherapy.Material and ...
Cunha, Adam, Diederich, Chris, Hsu, I-Chow, Mellis, Katherine, Pouliot, Jean, Sethi, Rajni, Siauw, Timmy   +6 more
core   +3 more sources