Results 31 to 40 of about 1,264,562 (211)
Endodontology, 2020 Aim: This study aims to evaluate and compare the canal transportation and centering ability of two nickel–titanium file systems, ProTaper Next and WaveOne Gold, in comparison with ProTaper Universal in mesiobuccal canals of maxillary molars using micro ...
Anuradha Vijay Sawardeker +3 more
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Procedural errors detected by cone beam tomography in cases with indication for retreatment: in vivo cross-sectional study [PDF]
Restorative Dentistry & EndodonticsObjectivesThis study aimed to investigate the frequency and type of endodontic procedural errors in cases indicated for retreatment through cone-beam computed tomography (CBCT) analysis.Materials and MethodsThe sample consisted of 96 CBCT scans ...
Henry Paul Valverde Haro +2 more
doaj +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Annali di StomatologiaBackground: Canal curvature is a major risk factor for canal transportation, which in turn causes that many parts of the root canal system remain untouched leading to persistence of microorganisms and debris, promoting structural weakening, and ...
Maya Eter, Roula S Abiad
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Indian Journal of Dental Research, 2022 Background: In comparison to multiple file systems, recent advancements in single file retreatment systems had reduced the working time and ease of operation for clinicians.
K Nanda Kishore +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Journal of the California Dental AssociationBackground Single-use endodontic NiTi rotary instruments reduce cross-contamination and fracture risks but are more costly. Reuse and sterilization may alter properties, impacting cutting efficiency and transportation.Methods NiTi rotary files underwent ...
Salar Motamedi +3 more
doaj +1 more source
Erbil Dental Journal, 2022 Background and objectives: one of the most important steps for root canal treatment is biomechanical preparation, which is the key stage of endodontic treatment with a predictive success factor if performed properly to prevent canal transportation.
Shakhawan Kadir Kadir
doaj