Results 81 to 90 of about 18,335 (163)

« Freins et moteurs à la recherche clinique. Une comparaison de trois essais académiques multicentriques [PDF]

, 2008
A travers la comparaison du déroulement de trois essais académiques et multicentriques, cette recherche, soutenue par l’INCa, s’inscrit dans la suite des travaux déjà menés par la PARCC-ARA pour comprendre les facteurs qui freinent et qui favorisent la ...
Castel, Patrick
core   +1 more source

SWI/SNF regulates a transcriptional programme that induces senescence to prevent liver cancer [PDF]

, 2016
Oncogene-induced senescence (OIS) is a potent tumour suppressor mechanism. To identify senescence regulators relevant to cancer, we screened an shRNA library targeting genes deleted in hepatocellular carcinoma (HCC).
Banito, A, Carroll, T, Deswal, S, Garcia-Escudero, R, Ghamarlingam, G, Gil, J, Gonzalez Meljem, JM, Hohmeyer, A, Khan, S, Klotz, S, Martin, N, Martinez-Barbero, JP, Pedro, J, Raguz, S, Tordella, L, Zender, L, Zuber, J   +16 more
core   +2 more sources

Issue Information

Cancer Medicine, Volume 15, Issue 5, May 2026.
wiley   +2 more sources

Profil Clinicopathologique et Devenir des Patientes Atteintes d'un Cancer du Sein non Métastatique à Abidjan

Health Research in Africa
RÉSUMÉ Introduction. Le cancer du sein représente un défi de santé publique croissant en Afrique subsaharienne, souvent diagnostiqué à un stade avancé. En Côte d'Ivoire, bien que les efforts d'équipement et de sensibilisation améliorent le diagnostic de
Mébiala NMP, Touré PGLK, Odo BA, Touré YL, Sességnon FA, Nobou AMBY, Madiou MKA, Touré M   +7 more
doaj   +1 more source

Intensity-modulated radiation therapy from 70Gy to 80Gy in prostate cancer: six- year outcomes and predictors of late toxicity

Radiation Oncology, 2017
Objective To report grade ≥2 overall late rectal and urinary toxicities in patients (pts) with prostate cancer treated by intensity-modulated radiotherapy (IMRT) at 3 dose-levels.
Maria Jolnerovski, Julia Salleron, Véronique Beckendorf, Didier Peiffert, Anne-Sophie Baumann, Valérie Bernier, Sandrine Huger, Vincent Marchesi, Ciprian Chira   +8 more
doaj   +1 more source

SAF-A / hnRNP U : une protéine à l'interface du métabolisme de l'ARN et des dommages à l'ADN [PDF]

, 2013
Des connexions entre la réponse aux dommages à l'ADN et le métabolisme de l'ARN ont récemment été mises en évidence. Mon équipe a identifié une protéine de liaison à l'ARN, SAF-A/hnRNP U, comme un substrat de la DNA-PK, kinase clé de la réparation des ...
Dernoncourt, Emma
core  

Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis [PDF]

, 2016
Despite the well-established tumor suppressive role of TGFβ proteins, depletion of key TGFβ signaling components in the mouse ovary does not induce a growth advantage.
Bartholin, Laurent, Davis, Anna Jane, Gao, Yang, Li, Qinglei, Sansom, Owen, Vincent, David   +5 more
core   +1 more source

Can inter-observer consistency be achieved in the laparoscopic assessment of the peritoneal carcinomatosis index score in peritoneal metastasis? A pilot study

Pleura and Peritoneum
The main prognostic factor for peritoneal metastasis (PM) is the complete resection of the disease during cytoreductive surgery. Accurate patient selection is therefore essential for determining eligibility for this type of surgery.
Astruc Audrey, Seegers Valérie, Dumont Frederic, Loaec Cécile, Thibaudeau Emilie, Bourgin Charlotte, Wernert Romuald, Body Noémie, De Franco Valeria   +8 more
doaj   +1 more source

The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial Cells

Neoplasia: An International Journal for Oncology Research, 2016
The TWIST1 embryonic transcription factor displays biphasic functions during the course of carcinogenesis. It facilitates the escape of cells from oncogene-induced fail-safe programs (senescence, apoptosis) and their consequent neoplastic transformation.
Laurent Jacqueroud, Charlotte Bouard, Geoffrey Richard, Léa Payen, Mojgan Devouassoux-Shisheboran, Douglas B. Spicer, Julie Caramel, Guillaume Collin, Alain Puisieux, Agnès Tissier, Stéphane Ansieau   +10 more
doaj   +1 more source

Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatment

BMC Cancer, 2018
Background The irinotecan-induced phosphokinome changes in colorectal cancer (CRC) cells were used to guide the selection of targeted agents to be tested in combination with irinotecan.
Diego Tosi, Esther Pérez-Gracia, Salima Atis, Nadia Vié, Eve Combès, Mélissa Gabanou, Christel Larbouret, Marta Jarlier, Caroline Mollevi, Adeline Torro, Maguy Del Rio, Pierre Martineau, Céline Gongora   +12 more
doaj   +1 more source