Results 111 to 120 of about 7,224,511 (260)

Cancer in Ireland 1994-2014: Annual Report of the National Cancer Registry

, 2016
This is the 21st annual statistical report of the National Cancer Registry. The report summarises cancer incidence, mortality and survival in Ireland for the period 1994 to 2014.
National Cancer Registry Ireland (NCRI)
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Streamlining Detection of Fusion Genes in Colorectal Cancer: Having "Faith" in Precision Oncology in the (Tissue) "Agnostic" Era.

, 2019
The FDA recently granted tissue-agnostic approval for the first-in-class TRK inhibitor larotrectinib for patients whose tumors harbor fusions in neurotrophic receptor tyrosine kinases.
Valeri, N
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Highlights of prostate cancer research in Ireland

, 2010
Summary document highlighting prostate cancer research in Ireland.The publication of this report was supported by an educational grant from ...
Prostate Cancer Research Consortium
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Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cancer in Ireland 1994-2001: incidence,mortality and treatment: a report from the National Cancer Registry

, 2005
National Cancer Registry ...
National Cancer Registry Ireland (NCRI)
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The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.

UNLABELLED: Analysis of DNA methylation is a valuable tool to understand disease progression and is increasingly being used to create diagnostic and prognostic clinical biomarkers.
Sjöström, M, Ning, Y, Witte, ON, Boutros, PC, Huang, FW, Perry, MD, Gleave, M, Zwart, W, Shrestha, R, Phillips, T, Maher, CA, He, HH, Aggarwal, R, Fraser, M, Petricca, J, Small, EJ, Quigley, DA, Bjartell, A, Ye, W, Morgans, AK, Ashworth, A, Maurice-Dror, C, Ng, SWS, Moreno-Rodriguez, T, Haffner, MC, Levy, S, Beer, TM, Gilbert, LA, Zhao, SG, Fong, L, Rettig, MB, Annala, M, Bose, R, He, C, Lloyd, P, Mahajan, NP, Cui, X-L, McCarthy, E, Chou, J, Hua, JT, Evans, CP, Feng, FY, Li, H, Chen, S, Chen, WS, Foye, A, Zoubeidi, A, Chi, KN, Lang, JM, Bergamaschi, A, Chesner, L, Tran, PT, Lundberg, A, Herberts, C, Posadas, EM, Wyatt, AW, Luo, J, Maheshwari, A, Zhang, M, Thomas, GV, Huang, J, Reiter, RE, Alumkal, JJ, Lara, PN   +63 more
core   +1 more source

Goodman Cancer Institute Research Symposium

McGill Journal of Medicine, 2022
Goodman Cancer Institute
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Metastatic breast cancer in Ireland: a National Cancer Registry Analysis 2024 [PDF]

The information presented here uses NCRI data to broadly describe the metastatic breast cancer (MBC) disease pattern from 1994 to 2018 in Ireland, with particular reference to the years 2005-2018.
National Cancer Registry Ireland (NCRI)
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