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Cancer Clinical Trials Optimization and Pharmacogenomics [PDF]
, 2012 A critical overview of recent clinical trials in cancer is presented focused on signaling pathways blockers or inhibitors with a view to developing successful clinical trials employing personalized cancer therapies.
I. C. Baianu
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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Chinese expert consensus on whole-process management of chemotherapy-related diarrhea (2025 edition) [PDF]
Zhongguo aizheng zazhiChemotherapy is a critical treatment modality for cancer, playing an essential role in oncology. However, chemotherapy-related diarrhea (CRD) remains a troubling adverse effect, often leading to reduced chemotherapy doses, treatment delays or ...
China Anti-Cancer Association Committee of Rehabilitation and Palliative Care, Fujian Anti-Cancer Association Committee of Cancer Pain
doaj +1 more source
Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment [PDF]
, 2015 Cancer is a complex, multiscale process involving interactions at intracellular, intercellular and tissue scales that are in turn susceptible to microenvironmental changes.
Chaplain, Mark Andrew Joseph +1 more
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FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
THE CANCER PROBLEM AND CANCER RESEARCH. [PDF]
The Lancet, 1905 n ...
Beard, J., Shaw-Mackenzie, JohnA
openaire +3 more sources
Frontiers in Endocrinology, 2011 The hypothesis that diabetes mellitus (DM) is associated with an increased risk of cancer is a deep-rooted suggestion, formulated probably during nineteenth century, surely very far away from knowledge of the pathogenic mechanisms of both diseases. Nowadays, numerous meta-analysis demonstrate the strong positive correlation existing between DM and site-
COLAO, ANNAMARIA +2 more
openaire +6 more sources
Business Systems ResearchWhen pairwise comparisons are used to express preferences for alternatives or judgments on criteria's importance, several methods can be used to derive priorities in multi-criteria decision-making.
Čančer Vesna
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A systematic literature review: the effect of date palms (phoenix dactylifera) toward breast cancer MCF-7 cell line. [PDF]
, 2021 Breast cancer is most significant diagnosed cancer in women that approximately 2.1 millions women were diagnosed with breast cancer and caused 627,000 deaths worldwide in 2018 based on Press Release 2018 from International Agency for Research on Cancer ...
Abdullah, Teo Wee Siang@Aariz Daniel Teo +3 more
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