Results 41 to 50 of about 11,034,909 (369)
Understanding genomic alterations in cancer genomes using an integrative network approach [PDF]
, 2014 In recent years, cancer genome sequencing and other high-throughput studies of cancer genomes have generated many notable discoveries. In this review, Novel genomic alteration mechanisms, such as chromothripsis (chromosomal crisis) and kataegis (mutation storms), and their implications for cancer are discussed.
arxiv +1 more source
Data-integration with pseudoweights and survey-calibration: application to developing US-representative lung cancer risk models for use in screening [PDF]
arXiv, 2023 Accurate cancer risk estimation is crucial to clinical decision-making, such as identifying high-risk people for screening. However, most existing cancer risk models incorporate data from epidemiologic studies, which usually cannot represent the target population.
arxiv
The 150 most important questions in cancer research and clinical oncology series: questions 15–24
Chinese Journal of Cancer, 2017 To accelerate our endeavors to overcome cancer, Chinese Journal of Cancer has launched a program of publishing 150 most important questions in cancer research and clinical oncology. In this article, 10 more questions are presented as follows. Question 15:
Chinese Journal of Cancer
doaj +1 more source
Predictive genomics: A cancer hallmark network framework for predicting tumor clinical phenotypes using genome sequencing data [PDF]
, 2014 We discuss a cancer hallmark network framework for modelling genome-sequencing data to predict cancer clonal evolution and associated clinical phenotypes. Strategies of using this framework in conjunction with genome sequencing data in an attempt to predict personalized drug targets, drug resistance, and metastasis for a cancer patient, as well as ...
arxiv +1 more source
Frontiers in Endocrinology, 2011 The hypothesis that diabetes mellitus (DM) is associated with an increased risk of cancer is a deep-rooted suggestion, formulated probably during nineteenth century, surely very far away from knowledge of the pathogenic mechanisms of both diseases. Nowadays, numerous meta-analysis demonstrate the strong positive correlation existing between DM and site-
COLAO, ANNAMARIA +2 more
openaire +6 more sources
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
The 150 most important questions in cancer research and clinical oncology series: questions 50–56
Chinese Journal of Cancer, 2017 Since the beginning of 2017, Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology, which sparkle diverse thoughts, interesting communications, and potential collaborations among researchers all ...
Chinese Journal of Cancer
doaj +1 more source
Avances en Supervisión Educativa, 2020 Editor: Pedro L. Moreno Martínez Editorial: Tirant lo Blanch, Valencia Año de edición: octubre 2018, primera edición Páginas: 455 Formato papel: Tapa blanda, 15 x 21 cm.
María del Pilar Cancer Pomar
doaj +1 more source
Ligand recognition by 14‐3‐3 proteins requires negative charges but not necessarily phosphorylation
FEBS Letters, Volume 599, Issue 6, Page 838-847, March 2025.Interactions of 14‐3‐3 proteins with their binding partners are attributed to phosphorylation of the binding partners. In this work, we show that at least one negative charge is required for the peptides to bind 14‐3‐3ε, although phosphorylation is not necessary, and that two negative charges are preferable for high affinity binding.
Seraphine Kamayirese +2 more
wiley +1 more source
Rare Tumors, 2015 To date, the Rare Cancer Network (RCN) has initiated more than 90 studies and 54 peer-reviewed publications were produced as a result. The Second International Symposium of the Rare Cancer Network recently took place in Istanbul, Turkey on April 17-18 ...
The Rare Cancer Network
doaj +1 more source