Results 71 to 80 of about 3,851,581 (260)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The 150 most important questions in cancer research and clinical oncology series: questions 6–14
Chinese Journal of Cancer, 2017 To accelerate our endeavors to overcome cancer, Chinese Journal of Cancer has launched a program of publishing 150 most important questions in cancer research and clinical oncology. In this article, nine more questions are presented as followed. Question
Chinese Journal of Cancer
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
El alud de peña gabarda (balneario de Panticosa, Huesca) del dos de marzo de 2001
Investigaciones Geográficas, 2002 El alud producido en la vertiente ESE de Peña Gabarda, cerca del Balneario de Pan-ticosa (Pirineo central, provincia de Huesca, España) en la mañana del dos de marzo de2001, se deslizó sobre una canal donde la frecuencia de aludes es muy alta y en la que
Luis Cancer Pomar
doaj
The 150 most important questions in cancer research and clinical oncology series: questions 31–39
Chinese Journal of Cancer, 2017 To accelerate our endeavors to overcome cancer, Chinese Journal of Cancer has launched a program of publishing 150 most important questions in cancer research and clinical oncology. In this article, 9 more questions are presented as follows. Question 31:
Chinese Journal of Cancer
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The 150 most important questions in cancer research and clinical oncology series: questions 40–49
Chinese Journal of Cancer, 2017 Since the beginning of 2017, Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology, which sparkle diverse thoughts, interesting communications, and potential collaborations among researchers all ...
Chinese Journal of Cancer
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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JMIR Cancer, 2015 BackgroundThe benefits of physical activity for cancer survivors are well documented. However, few older cancer survivors are engaged in regular physical activity.
Hong, Yan Alicia +6 more
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