Results 201 to 210 of about 3,139,231 (313)

Toward a multi-level, needs-based approach to cancer navigation: Considerations for service design. [PDF]

Support Care Cancer
Thamm C, Bender J, Agbejule OA, Ramsey I, Crawford-Williams F, Ee C, McComb K, Agrawal AK, Chan RJ.   +8 more
europepmc   +1 more source

Additional file 3: Table S1. of Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors

, 2017
Stephan Bernhardt, Michaela BayerlovĂĄ, Martina Vetter, Astrid Wachter, Devina Mitra, Volker Hanf, Tilmann Lantzsch, Christoph Uleer, Susanne Peschel, Jutta John, JĂśrg Buchmann, Edith Weigert, Karl-Friedrich BĂźrrig, Christoph Thomssen, Ulrike Korf, Tim Beißbarth, Stefan Wiemann, Eva Johanna Kantelhardt   +17 more
openalex   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Top 10 research priorities for adolescent and young adult cancer in Canada: a James Lind Alliance priority setting partnership. [PDF]

BMJ Open
Tutelman PR, Thurston C, Ranger T, Rader T, Henry B, Abdelaal M, Blue M, Buckland TW, Del Gobbo S, Dobson L, Gallant E, Heykoop C, Jansen M, Larsen L, Maseja N, Oberoi S, Ramasamy V, Smith M, Wendowsky N, Beattie S, Bender JL, Birnie K, Garland SN, Jibb L, Noel M, Schulte FSM.   +25 more
europepmc   +1 more source

Cancer Antigen 15-3 [PDF]

, 2019
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Economic Evaluation of GARDE: A Digital Health Platform for Population-Level Hereditary Cancer Risk Assessment. [PDF]

JCO Oncol Pract
Ahsan MD, Kaphingst KA, Kohlmann WK, Bradshaw RL, Allen CG, Schlechter C, Kukhareva P, Maxwell W, Martin C, Davis-Rivera L, Madeo AC, Borsato EP, Frey MK, Kawamoto K, Fiol GD, Elkin EB, Sharaf RN.   +16 more
europepmc   +1 more source

Prostate Cancer Antigene 3 [PDF]

, 2018
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source