Results 251 to 260 of about 479,049 (311)

Healthcare providers' awareness, perceptions and experiences in integrating palliative care for women with HIV and cancer in Nigeria: a qualitative study on barriers and facilitators. [PDF]

BMC Health Serv Res
Idemili-Aronu N, Okoli IA, Jemisenia JO, Olawepo JO, Onyeka T, Ezeanolue EE.   +5 more
europepmc   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

The role of healthcare providers in shared decision making for cervical cancer prevention in Ghana: A qualitative study. [PDF]

BMC Cancer
Bonnah J, Awuah B, Williams MS.
europepmc   +1 more source

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source

A facility level cross-sectional survey to assess health system readiness for oral cancer care in Madhya Pradesh, India. [PDF]

Bioinformation
Anwar S, Majumdar A, Sabde YD, Goel P, Kumar S, Khurana U.   +5 more
europepmc   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Strengthening Public Policy to Address the Financial Burden of Breast Cancer Care in Nigeria: A Critical Imperative. [PDF]

Cancer Control
Ajala DE, Ogunmodede EO, Ishola RO.
europepmc   +1 more source

Assessing the covariates of delay in seeking health care among patients with oral and oropharyngeal squamous cell carcinoma in Tanzania. [PDF]

BMC Cancer
Owibingire SS, Minja IK, Simon EN, Costea DE, Astrom AN.   +4 more
europepmc   +1 more source

Regional disparities in lymphedema treatment and access to complex decongestive therapy: a nationwide survey in Japan. [PDF]

Jpn J Clin Oncol
Masujima M, Akita S, Tazaki M, Tsujimoto A, Katagiri R, Yasuda C, Tsuji T.   +6 more
europepmc   +1 more source

Trends and factors associated with hospice care utilization and place of death in the United States between 2002 and 2020: a retrospective data analysis based on the health and retirement study. [PDF]

BMC Palliat Care
Long Y, Tan M, Xia Q, Xu Z, Ding J.
europepmc   +1 more source