Results 31 to 40 of about 708,374 (219)

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

MicroAIbiome: Decoding Cancer Types from Microbial Profiles Using Explainable Machine Learning

open access: yesMicroorganisms
Microbial communities within human tissues are increasingly recognized as promising biomarkers for cancer detection. However, leveraging microbiome data for multiclass cancer classification remains challenging due to its compositional structure, high ...
Md Motiur Rahman   +5 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier   +10 more
wiley   +1 more source

Explainable Artificial Intelligence (XAI) for Cancer Classification in Medical Imaging: A Systematic Review

open access: yesMachine Learning and Knowledge Extraction
Our study examines the growing role of Explainable Artificial Intelligence (XAI) in cancer medical imaging, where transparency and interpretability are essential for trustworthy clinical decision making. Using a PRISMA-guided systematic literature review,
Khairil Imran Ghauth   +1 more
doaj   +1 more source

Pan-Cancer Classification Based on Self-Normalizing Neural Networks and Feature Selection

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Cancer is a one of the severest diseases and cancer classification plays an important role in cancer diagnosis and treatment. Some different cancers even have similar molecular features such as DNA copy number variant.
Junyi Li   +4 more
doaj   +1 more source

Assessment of Aspartame (E951) Occurrence in Selected Foods and Beverages on the German Market 2000–2022

open access: yesFoods, 2023
This study examines the occurrence of the artificial sweetener aspartame (E951) in foods and beverages sampled by food control authorities in Germany between 2000 and 2022. The dataset was obtained through the Consumer Information Act.
Sydney Schorb   +7 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot   +6 more
wiley   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei   +17 more
wiley   +1 more source

The consensus immunoscore: toward a new classification of colorectal cancer

open access: yesOncoImmunology, 2020
In its latest edition, the WHO classification of the Digestive System Tumors introduced for the first time the immune response as essential and desirable diagnostic criteria for colorectal cancer.
Anastasia Lanzi   +3 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

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