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Chinese experts consensus on quality control standards for tumor organoids diagnosis and treatment platform (2022 version) [PDF]
Zhongguo aizheng zazhi, 2022 Recently, advances in organoid technology have opened new avenues for the development of novel models of human cancer. Patient-derived tumor organoids retain phenotypes such as histopathological, genetic and molecular features of the original tumor.
The Society of Cancer Multidisciplinary Diagnosis and Treatment, China Anti-Cancer Association, The Society of Cancer Endocrinology, China Anti-Cancer Association
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Expert consensus on diagnosis, treatment and fertility management of young breast cancer patients
Journal of the National Cancer Center, 2021 Breast cancer in young females is a relatively common disease in China. Young breast cancer has aggressive clinical and pathological features. During the treatment of young females with breast cancer, issues involving the choice of surgical methods ...
Committee of Diagnosis, Treatment, and Fertility Management of Chinese Young Breast Cancer Patients
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DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors
Scientific Reports, 2023 Role of DNA damage and demethylation on anticancer activity of DNA methyltransferase inhibitors (DNMTi) remains undefined. We report the effects of DNMT1 gene deletion/disruption (DNMT1 −/− ) on anticancer activity of a class of DNMTi in vitro, in vivo ...
Angelo B. A. Laranjeira +5 more
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Rethinking Oncologic Treatment Strategies with Interleukin-2
Cells, 2023 High-dose recombinant human IL-2 (rhIL-2, aldesleukin) emerged as an important treatment option for selected patients with metastatic melanoma and metastatic renal cell carcinoma, producing durable and long-lasting antitumor responses in a small fraction
Brian Ko +4 more
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Diagnosis of ovarian cancer [PDF]
BMJ, 2015 #### The bottom line Ovarian cancer is the seventh most common cancer in women worldwide, with 239 000 new cases diagnosed in 2012.1 As with many other types of cancer, geographical variation in the incidence of and mortality from ovarian cancer is substantial, with a higher incidence in economically developed regions of the world.2 Incidence is ...
Sundar, S, Neal, RD, Kehoe, S
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China National Lung Cancer Screening Guideline with Low-dose Computed Tomography (2023 Version)
Chinese Journal of Lung Cancer, 2023 Lung cancer is the leading cause of cancer-related death in China. The effectiveness of low-dose computed tomography (LDCT) screening has been further validated in recent years, and significant progress has been made in research on identifying high-risk ...
Chinese Expert Group on Early Diagnosis and Treatment of Lung Cancer +1 more
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Effects of MRE11 on Apoptosis and Proliferation of Esophageal Squamous Cancer Cells
Zhongliu Fangzhi Yanjiu, 2022 Objective To investigate the effect of MRE11 on the proliferation and apoptosis of esophageal squamous cancer cells and its molecular mechanism. Methods MRE11 expression was downregulated by MRE11 siRNA transfection in esophageal squamous cancer cells ...
ZHANG Yan +4 more
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Journal of Hematology & Oncology, 2021 Background Challenges remain on the selection of patients who potentially respond to a class of drugs that target epigenetics for cancer treatment. This study aims to investigate TET2/DNMT3A mutations and antitumor activity of a novel epigenetic agent in
Sherry X. Yang +7 more
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The Society of Cancer Precision Medicine of Chinese Anti-Cancer Association
Chinese Journal of Lung Cancer, 2023 RNA-based next-generation sequencing (NGS) has been recommended as a method for detecting fusion genes in non-small cell lung cancer (NSCLC) according to clinical practice guidelines and expert consensus.
China Primary Health Care Foundation Tumor Precision Diagnosis and Treatment Committee +1 more
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