Results 111 to 120 of about 6,665,898 (305)

Can non-contrast magnetic resonance imaging replace contrast-enhanced computerized tomography in the local staging of pediatric renal tumors?

The Egyptian Journal of Radiology and Nuclear Medicine
Background Renal tumors account for approximately 6–7% of the total incidence of pediatric cancers. Wilms tumor (WT) is the most common renal malignancy observed in the pediatric population under 5 years old.
Marwa Romeih, Mary Rabea Mahrous, Tarek Ahmed Raafat, Esmat Mahmoud   +3 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

The diagnosis of cancer of the lung.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2000
No Abstract.
openaire   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Root Cause Analysis of Patients with Pancreatic Cancer Who Underwent Imaging Not Resulting in a Cancer Diagnosis in the 18 Months Prior to Diagnosis

Purpose: Root cause analysis carried out to establish the likely causes for pancreatic cancer not being diagnosed on previous imaging. Methods: Records of pancreatic cancer patients between 2016 and 2021 at two NHS providers were examined.
Nosheen Umar, Brinder Mahon, Raneem Albazaz, Shahd A. Mohamed, Melisa Sia, Sumedha Udumalagala, Keith Roberts, Justin Smyth, Nigel Trudgill, Mujeeb Ullahj Makki, Trudgill, Nigel, Umar, Nosheen, Smyth, Justin, Albazaz, Raneem, Makki, Mujeeb Ullahj, Roberts, Keith, Mahon, Brinder, Udumalagala, Sumedha, Sia, Melisa, Mohamed, Shahd A   +19 more
core   +1 more source

ARHGAP11A, a member of Rho GTPase activating protein family, as a prognostic biomarker linked to DNA damage response across pan-cancer

BMC Cancer
Background The Rho GTPase-activating protein (RhoGAP) family represents a large and diverse group of proteins that act as key regulators of Rho GTPases, small GTP-binding proteins involved in cellular signaling. Tight regulation of Rho GTPase activity is
Ke Tan, Yun Wu, Jiaqi Zhang, Yuqiong Ding, Chen Cheng, Zhenyu Yan, Xuetong Wang, Liyuan Zhang   +7 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Cancer Trends: Primary Liver Cancer

, 2016
During 2012-2014, a little over half (58%) of all primary liver cancers were histologically confirmed, 37% were diagnosed radiologically only via x-ray, MRI/CT scan etc. and 5% did not have a method of diagnosis specified.
National Cancer Registry Ireland (NCRI)
core  

National Awareness And Early Diagnosis Initiative: Cancer Awareness Measure, Arden Cancer Network, 2009

, 2011
copyright UK Data Service and data collection copyright owner.The Cancer Awareness Measure (CAM) was developed in 2007-8 to address the absence of a validated measure of general public awareness of cancer (Stubbings, S., Robb, K., Waller, J., Ramirez, A.,
Public Knowledge, Arden Cancer Network
core   +3 more sources

Loss of Brg1 prevents the progression of pulmonary hypertension by inhibiting Nrf2 expression

Scientific Reports
Brahma-related gene 1 (Brg1) is a major factor in regulation of chromatin remodeling and is involved in different cellular processes, including cell proliferation, apoptosis, and differentiation. However, the role of Brg1 in pulmonary artery hypertension
Wen-Di Jiang, Mei-Yang Xu, Zi-yi Chen, Qing Chen, Guo-Qing Lu, Zheng-Yu Sun, Jia-Yi Guo, Lei Wang, Ying Qian, Li Mu, Yu-Hang Wang, Ning-ning Zhang, Hong-Ju Wang, Bi Tang, Pin-Fang Kang, Wen-Juan Wu   +15 more
doaj   +1 more source