Results 121 to 130 of about 12,916,683 (299)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Facteurs psychosociaux associés à l’intention de pratiquer régulièrement des activités physiques modérées chez les survivantes du cancer du sein. [PDF]
Can Oncol Nurs J, 2022 Lévesque-Gagné C, Boucher D.
europepmc +1 more source
Inflammation et risque de cancer du sein dans la cohorte EPIC
, 2020 Chronic inflammation might promote breast cancer development. Therefore, the possibility of stemming tumorigenic inflammatory effects with pharmacological compounds has drawn significant interest.
Cairat, Manon
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
[Triple negative breast cancer: clinical, pathological and molecular characteristics]. [PDF]
Pan Afr Med J, 2022 Hammouda SB +5 more
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Stratégie d’adaptation et typologie du soutien social perçu chez les partenaires masculins de femmes atteintes d’un cancer du sein. [PDF]
Can Oncol Nurs J, 2022 Cheng T +3 more
europepmc +1 more source
Cancer Trends: Cancers of the testis
, 2012 An average of 132 cases of testicular cancer was diagnosed per year in Ireland between 1994 and 2010 (Table 1). Almost all cases were microscopically verified (98%) and were germ-cell tumours—57% of which were seminomatous and 40% non-seminomatous ...
National Cancer Registry Ireland (NCRI)
core
Facteurs de risque du cancer du sein
, 2005 Le cancer du sein est une préoccupation majeure de santé publique. En 2001, plus d’un million de nouveaux cas et 372 969 décès attribuables au cancer du sein ont été enregistrés dans le monde.
Ghadirian, Parviz +3 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source