Results 161 to 170 of about 274,173 (312)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Optimizing accuracy and dimensionality: a swarm intelligence strategy for robust cancer genomics classification. [PDF]

BioData Min
Yaqoob A, Mir MA, Lakshmi RV, Pradhan T, Rao GVVJ, Tejani GG, Shah MA.   +6 more
europepmc   +1 more source

Leading the pack: Best practices in comparative canine cancer genomics to inform human oncology. [PDF]

Vet Comp Oncol, 2023
London CA, Gardner H, Zhao S, Knapp DW, Utturkar SM, Duval DL, Chambers MR, Ostrander E, Trent JM, Kuffel G.   +9 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Towards Precision Oncology: How Advances in Cancer Genomics, Immunobiology and Artificial Intelligence Will Change Molecular Diagnostics. [PDF]

Biomedicines
Izevbaye I.
europepmc   +1 more source

Genomic Landscape of Endometrial, Ovarian, and Cervical Cancers in Japan from the Database in the Center for Cancer Genomics and Advanced Therapeutics. [PDF]

Cancers (Basel), 2023
Xi Q, Kage H, Ogawa M, Matsunaga A, Nishijima A, Sone K, Kawana K, Oda K.   +7 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Accelerating cancer genomics research in Sub-Saharan Africa. [PDF]

Front Oncol
Ivanga M, Iroungou BA, Bigoundou-Nzamba S, Bisseye C.   +3 more
europepmc   +1 more source

Editorial: Prostate cancer genomics: Application at different stages of a patient's journey. [PDF]

Front Oncol, 2022
Poon DMC, Azad A, Castro E, Kanesvaran R, Sartor O.   +4 more
europepmc   +1 more source

Genomic biomarkers to guide precision radiotherapy in prostate cancer

, 2022
Philip Sutera, Matthew P. Deek, Kim Van der Eecken, Alexander W. Wyatt, Amar U. Kishan, Jason K. Molitoris, Matthew J. Ferris, M. Minhaj Siddiqui, Zaker Rana, Mark V. Mishra, Young Kwok, Elai Davicioni, Daniel E. Spratt, Piet Ost, Felix Y. Feng, Phuoc T. Tran   +15 more
openalex   +2 more sources