Results 191 to 200 of about 5,135,152 (380)

EXPANSION: a webserver to explore the functional consequences of protein-coding alternative splice variants in cancer genomics. [PDF]

Bioinform Adv, 2023
Arora C, De Oliveira Rosa N, Matic M, Cascone M, Miglionico P, Raimondi F.   +5 more
europepmc   +1 more source

Genomic loci susceptible to replication errors in cancer cells

, 1998
Maja Krajinović, Chantal Richer, Izabella Gorska‐Flipot, Louis Gaboury, Ivana Novaković, Damian Labuda, Daniel Sinnett   +6 more
openalex   +1 more source

High-performance capillary electrophoretic method for the quantification of 5-methyl 2'-deoxycytidine in genomic DNA: Application to plant, animal and human cancer tissues [PDF]

, 2002
Mario F. Fraga, E. Uriol, L. B. Diego, María Berdasco, Manel Esteller, María Jesús Cañal, Roberto Rodrı́guez   +6 more
openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

The Crucial Findings Derived from the Special Issue "Inside Cancer Genomics: From Structure to Therapy". [PDF]

Cancers (Basel), 2023
Barresi V.
europepmc   +1 more source

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer [PDF]

, 2002
Hiromu Suzuki, Edward Gabrielson, Wei Chen, Ramaswamy Anbazhagan, Manon van Engeland, Matty P. Weijenberg, James G. Herman, Stephen B. Baylin   +7 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Editorial: Prostate cancer genomics: Application at different stages of a patient's journey. [PDF]

Front Oncol, 2022
Poon DMC, Azad A, Castro E, Kanesvaran R, Sartor O.   +4 more
europepmc   +1 more source

Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach [PDF]

, 2002
Gilles Thomas, Frans B.L. Hogervorst, Gerard Pals, Juul Wijnen, R J van Schooten, Charlotte J. Dommering, Gerrit A. Meijer, M. E. Craanen, Petra M. Nederlof, Daphne de Jong, Cathal J. McElgunn, Jan P. Schouten, Fred H. Menko   +12 more
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source