Results 191 to 200 of about 274,173 (312)

Beyond the ruler: Measuring what truly matters in endoscopic ultrasound-guided pancreatic cancer genomics. [PDF]

Endosc Int Open
Wu J, Wang W, Yang K.
europepmc   +1 more source

Towards routine chromosome-scale haplotype-resolved reconstruction in cancer genomics. [PDF]

Nat Commun, 2023
Garg S.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Deep learning-driven drug response prediction and mechanistic insights in cancer genomics. [PDF]

Sci Rep
Yu G, Fan Q.
europepmc   +1 more source

Multi-omics Pathways Workflow (MOPAW): An Automated Multi-omics Workflow on the Cancer Genomics Cloud. [PDF]

Cancer Inform, 2023
Nguyen T, Bian X, Roberson D, Khanna R, Chen Q, Yan C, Beck R, Worman Z, Meerzaman D.   +8 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Clinical reporting for personalized cancer genomics requires extensive access to subscription-only literature. [PDF]

J Med Libr Assoc, 2023
D'Souza S, Downs G, Hendrikx S, Fazelzad R, Boldt G, Burns K, Chapman D, Dawes D, Giannarakos A, Oja LA, Schorr R, Babb M, Hodgson A, McEwan J, Jacobs P, Stockley T, Tripp T, King I.   +17 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Precision medicine in colorectal cancer: genomics profiling and targeted treatment. [PDF]

Front Pharmacol
Muradi Muhar A, Velaro AJ, Prananda AT, Nugraha SE, Halim P, Syahputra RA.   +5 more
europepmc   +1 more source

Breast Cancer Genomics: Primary and Most Common Metastases. [PDF]

Cancers (Basel), 2022
Bennett C, Carroll C, Wright C, Awad B, Park JM, Farmer M, Brown EB, Heatherly A, Woodard S.   +8 more
europepmc   +1 more source