Results 201 to 210 of about 5,135,152 (380)

Imaging genomics of cancer: a bibliometric analysis and review

Cancer Imaging
Background Imaging genomics is a burgeoning field that seeks to connections between medical imaging and genomic features. It has been widely applied to explore heterogeneity and predict responsiveness and disease progression in cancer.
Xinyi Gou, Aobo Feng, Caizhen Feng, Jin Cheng, Nan Hong   +4 more
doaj   +1 more source

Multi-omics Pathways Workflow (MOPAW): An Automated Multi-omics Workflow on the Cancer Genomics Cloud. [PDF]

Cancer Inform, 2023
Nguyen T, Bian X, Roberson D, Khanna R, Chen Q, Yan C, Beck R, Worman Z, Meerzaman D.   +8 more
europepmc   +1 more source

Target validation for genomics using peptide‐specific phage antibodies: A study of five gene products overexpressed in colorectal cancer [PDF]

, 2002
Judy R. van Beijnum, Peter T.M. Moerkerk, Andrea J. Gerbers, Adriaan P. de Bruı̈ne, Jan‐Willem Arends, Hennie R. Hoogenboom, Simon E. Hufton   +6 more
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Towards routine chromosome-scale haplotype-resolved reconstruction in cancer genomics. [PDF]

Nat Commun, 2023
Garg S.
europepmc   +1 more source

bc10: A novel human bladder cancer‐associated protein with a conserved genomic structure downregulated in invasive cancer [PDF]

, 2002
Irina Gromova, Pavel Gromov, Julio E. Celis   +2 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Screening of Germline BRCA1 and BRCA2 Variants in Nigerian Breast Cancer Patients

Technology in Cancer Research & Treatment
Background Breast cancer remains a leading cause of mortality among Nigerian women, with triple-negative breast cancer (TNBC) being particularly prevalent. Variations in BRCA1 and BRCA2 genes remain key risk factors for this disease.
Abimbola F. Onyia MSc, Paul Jibrin MBBS, Temitope Olatunji-Agunbiade MBBS, Ademola Oyekan MBBS, AbdulRazzaq Lawal MBBS, Adewumi Alabi MBBS, Anthonia C. Sowunmi MBBS, Eben A. Aje MBBS, Oluwabusayo B. Ogunniyi MBBS, Ebenezer S. Nkom MBBS, Opeyemi C. De Campos PhD, Oluwakemi A. Rotimi PhD, Jelili O. Oyelade PhD, Solomon O. Rotimi PhD   +13 more
doaj   +1 more source

Discovering Combinations of Genomic Aberrations Associated With Cancer [PDF]

, 2002
Michael A. Newton
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source