Results 211 to 220 of about 5,135,152 (380)

Bioinformatics roadmap for therapy selection in cancer genomics. [PDF]

open access: yesMol Oncol, 2022
Jiménez-Santos MJ   +5 more
europepmc   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Clinical reporting for personalized cancer genomics requires extensive access to subscription-only literature. [PDF]

open access: yesJ Med Libr Assoc, 2023
D'Souza S   +17 more
europepmc   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Breast Cancer Genomics: Primary and Most Common Metastases. [PDF]

open access: yesCancers (Basel), 2022
Bennett C   +8 more
europepmc   +1 more source

Large-scale genomic instability predicts long-term outcome for women with invasive stage I ovarian cancer [PDF]

open access: bronze, 2003
Gunnar B. Kristensen   +6 more
openalex   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

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