Results 291 to 300 of about 5,135,152 (380)

Ovarian Function Restoration with Biomimetic Scaffold Incorporating Angiogenic Molecules and Antioxidant in Chemotherapy‐Induced Perimenopausal Model

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim   +8 more
wiley   +1 more source

Comparative functional genomics for identifying models of human cancer [PDF]

open access: hybrid, 2005
Ju‐Seog Lee   +2 more
openalex   +1 more source

Influence of Hypoxia on a Biomaterial Model of the Bone Marrow Perivascular Niche

open access: yesAdvanced Healthcare Materials, EarlyView.
Hypoxia is a key factor in bone marrow physiology and hematopoietic stem cell behavior. Lower oxygen tension influences the secretion of vasculature‐derived hematopoietic regulatory factors and alters hematopoietic cell behavior in a conditioned medium hydrogel model of bone marrow. Cyclosporin A is used to mitigate normoxic stress during hematopoietic
Gunnar B. Thompson   +3 more
wiley   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

open access: yesAdvanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu   +4 more
wiley   +1 more source

Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population

open access: bronze, 2005
Avraham Shaag   +12 more
openalex   +1 more source

Breast cancer genomics and immuno-oncological markers to guide immune therapies.

open access: yesSeminars in Cancer Biology, 2017
Dora Hammerl   +5 more
semanticscholar   +1 more source

Terahertz Metamaterial Sensors: Design Theory, Optimization Approach, and Advancements in Biosensing Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This review provides an in‐depth overview of the design principles and optimization strategies for terahertz (THz) metamaterials (MMs) sensors based on the dielectric perturbation theory. Various structures and methods are explored to enhance sensor performance, focusing on improving sensitivity and Q‐factor.
Lei Cao   +9 more
wiley   +1 more source

Investigating the Potential for Label‐Free Detection of Cell Apoptosis through Terahertz Nano‐Metasurfaces

open access: yesAdvanced Photonics Research, EarlyView.
This study demonstrates a label‐free optical method to monitor cells using a terahertz metasurface‐based biosensing platform. The obtained terahertz signal change for the cell‐contained nanoslots before and after external stimulus is analyzed in terms of transmittance and frequency shift, dynamically representing the cell apoptosis process.
Yeeun Roh   +4 more
wiley   +1 more source

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

open access: bronze, 2005
Sooryanarayana Varambally   +14 more
openalex   +1 more source

Frequency‐Dependent Demethylation of Cancer DNAs by High‐Power Terahertz Radiation

open access: yesAdvanced Photonics Research, EarlyView.
Effective demethylation of cancer DNA is successfully demonstrated by resonant irradiation with high‐power terahertz (THz) waves at the 10 mW level, combined with metamaterial‐based THz filters. The dependence of spectral filtering on demethylation indicates that the resonant frequency of 1.6 THz of cancer DNAs plays a crucial role in reducing the ...
Chaeyoon Kim   +8 more
wiley   +1 more source

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