Results 31 to 40 of about 274,173 (312)
Scientific Reports, 2022 This review aimed to examine the relationship between TP53 mutational status, as determined by genomic sequencing, and survival in squamous cell carcinoma of the head and neck.
Shadi Basyuni +11 more
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Cancer Cell, 2002 The draft human genome sequence and the dissemination of high throughput technology provides opportunities for systematic analysis of cancer cells. Genome-wide mutation screens, high resolution analysis of chromosomal abberations and expression profiling all give comprehensive views of genetic alterations in cancer cells.
openaire +2 more sources
Contextualization of drug-mediator relations using evidence networks
BMC Bioinformatics, 2017 Background Genomic analysis of drug response can provide unique insights into therapies that can be used to match the “right drug to the right patient.” However, the process of discovering such therapeutic insights using genomic data is not ...
Hai Joey Tran +3 more
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Genomic and epigenomic integrative subtypes of renal cell carcinoma in a Japanese cohort
Nature Communications, 2023 Renal cell carcinoma (RCC) comprises several histological types characterised by different genomic and epigenomic aberrations; however, the molecular pathogenesis of each type still requires further exploration.
Akihiko Fukagawa +10 more
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Acta Medica Academica, 2019 <p>The landscape of lung cancer treatment is rapidly evolving with the use of genomic testing which helps identify specific mutations or resistance mutations for these heterogenous tumors. Advanced lung cancer has a very poor prognosis but identifying other treatment options based on genomic profiling of the tumor can lead to improved outcomes ...
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Genomics of Prostate Cancer: Clinical Utility and Challenges
Acta Clinica Croatica, 2022 The studying of prostate cancer genomics is important for understanding prostate cancer biology, it can provide clinically relevant stratification into subtypes, the development of new prognostic and predictive markers in the context of precision ...
Ivan Šamija, Ana Fröbe
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Integrated genetic and epigenetic analysis of myxofibrosarcoma
Nature Communications, 2018 Myxofibrosarcoma occurs in adults and is associated with high local relapse. Here, based on exome/transcriptome sequencing and DNA methylation analysis, the authors identify driver genes and methylation clusters associated with unique combinations of ...
Koichi Ogura +14 more
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Authorship Patterns in Cancer Genomics Publications Across Africa
JCO Global Oncology, 2021 PURPOSEAuthorship is a proxy indicator of research capacity. Understanding the research capacity is imperative for developing population-specific cancer control strategies.
Solomon O. Rotimi +2 more
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Prostate cancer biology & genomics
Translational Andrology and Urology, 2020 Prostate Cancer is now the second biggest cause of cancer mortality in the UK. Media coverage has been rising, with some attributing to a rise in the cases diagnosed and treated in the NHS down to the "Fry and Turnbull effect". Our understanding of prostate cancer has increased tremendously in the past decades, with advances in molecular biology and ...
Whitaker, Hayley +3 more
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BMC Medical Genomics, 2018 Background Bladder cancer has numerous genomic features that are potentially actionable by targeted agents. Nevertheless, both pre-clinical and clinical research using molecular targeted agents have been very limited in bladder cancer. Results We created
Adnan Ahmad Ansari +5 more
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