Results 41 to 50 of about 274,173 (312)

Association Study between Folate Pathway Gene Single Nucleotide Polymorphisms and Gastric Cancer in Koreans [PDF]

open access: yesGenomics & Informatics, 2012
Gastric cancer is ranked as the most common cancer in Koreans. A recent molecular biological study about the folate pathway gene revealed the correlation with a couple of cancer types.
Jae-Young Yoo   +6 more
doaj   +1 more source

Selective therapeutic strategy for p53-deficient cancer by targeting dysregulation in DNA repair

open access: yesCommunications Biology, 2021
Zonneville et al. show that p53 mutant cancers express high levels of the Base Excision Repair (BER) pathway and that deoxyuridine analogues induce DNA damage in p53-mutant TNBC cells.
Justin Zonneville   +10 more
doaj   +1 more source

Massively parallel digital transcriptional profiling of single cells

open access: yesNature Communications, 2017
Single-cell gene expression analysis is challenging. This work describes a new droplet-based single cell RNA-seq platform capable of processing tens of thousands of cells across 8 independent samples in minutes, and demonstrates cellular subtypes and ...
Grace X. Y. Zheng   +32 more
doaj   +1 more source

NCI Workshop Report: Clinical and Computational Requirements for Correlating Imaging Phenotypes with Genomics Signatures

open access: yesTranslational Oncology, 2014
The National Cancer Institute (NCI) Cancer Imaging Program organized two related workshops on June 26–27, 2013, entitled “Correlating Imaging Phenotypes with Genomics Signatures Research” and “Scalable Computational Resources as Required for Imaging ...
Rivka Colen   +15 more
doaj   +1 more source

Genomics of Lung Cancer [PDF]

open access: yesProceedings of the American Thoracic Society, 2009
This review focuses on recent research using genomics to examine lung carcinogenesis, histologic differentiation, and progression.
Alain C, Borczuk   +2 more
openaire   +2 more sources

A qualitative study of genomics in cancer control for Aboriginal and Torres Strait Islander Australians

open access: yesAustralian and New Zealand Journal of Public Health
Objective: To describe the perspectives of Aboriginal and Torres Strait Islander peoples and health care workers on genomics in cancer care to inform the National Framework for Genomics in Cancer Control (the Framework). Methods: A total of 37 Aboriginal
Justine Clark   +9 more
doaj   +1 more source

VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer

open access: yesScientific Reports, 2017
Members of the mammalian Vestigial-like (VGLL) family of transcriptional cofactors activate genes in response to a wide variety of environmental cues.
Yinglong Zhang   +10 more
doaj   +1 more source

Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas

open access: yesNature Communications, 2018
Metabolism is frequently dysregulated in cancer. Here, the authors conduct a pan-cancer analysis of The Cancer Genome Atlas to determine significant metabolic pathway alterations, highlight master metabolic transcriptional regulators, and predict patient
S. R. Rosario   +5 more
doaj   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Data Mining Supercomputing with SAS JMP® Genomics [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2011
JMP® Genomics is statistical discovery software that can uncover meaningful patterns in high-throughput genomics and proteomics data. JMP® Genomics is designed for biologists, biostatisticians, statistical geneticists, and those engaged in analyzing the ...
Richard S. Segall   +2 more
doaj  

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