Results 211 to 220 of about 1,083,547 (307)

CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors

Advanced Science, EarlyView.
Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen, Xiaoyun Luo, Huixin Gao, Yujing Ke, Yu Zhan, Xiaoting Xu, Xiaoxiao Xiong, Fengjiao Wei, Si Yang, Zhonghua Liu, Bolan Yu, Zhaofeng Huang, Yingjie Bian   +12 more
wiley   +1 more source

Circulating Amino Acid Network Remodeling Reveals Systemic Metabolic Reprogramming Predictive of Colorectal Cancer Recurrence and Metastasis

Advanced Science, EarlyView.
Blood‐based amino acid patterns measured by 19F NMR reveal hidden metabolic changes in colorectal cancer. By analyzing how these amino acids interact as a network, machine learning models identify patients at higher risk of recurrence and metastasis.
Ji‐Yeon Lee, Jumi Kim, Taehan Yoon, So Hyun Kwon, Su Chan Park, Dohyun Chun, Dohyeong Kim, Eun Jung Park, Hyunwoo Kim, Ji Min Lee   +9 more
wiley   +1 more source

Epigenetic aging and cancer incidence in a German cohort of older adults. [PDF]

NPJ Aging
Yin Q, Stevenson-Hoare J, Holleczek B, Ben Schöttker, Brenner H.   +4 more
europepmc   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Risk of cancer incidence and mortality in patients with chronic pain: A systematic review and meta-analysis. [PDF]

Cancer Metastasis Rev
Lai CH, Hefteh N, Kingsford S, La Caze A, Sheikh M, Shrestha S, Parat MO.   +6 more
europepmc   +1 more source

Photothermal Amplification via Nanorobotic Swarming Dynamics

Advanced Science, EarlyView.
This study explores a novel approach to enhance photothermal therapy using magnetically regulated microswarms. It details the development of magnetic nanoparticles organized into dynamic structures that improve heat retention and conversion efficiency.
Qinglong Wang, Lin Su, Zhengxin Yang, Yihang Jiang, Haojin Yang, Qianqian Wang, Li Zhang, Ben Wang, Jiajia Wang   +8 more
wiley   +1 more source

Chronic High-Fat Diet Does Not Alter Overall Cancer Incidence in Trp53R270H/+ Mice. [PDF]

Cancer Res Commun
Panzeri I, Madaj ZB, Fagnocchi L, Apostle S, Tompkins M, Gallik K, Ma EH, Hostetter G, Jones RG, Pospisilik JA.   +9 more
europepmc   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

Cancer Incidence in Women After Medically Assisted Reproduction.

JAMA Netw Open
Vajdic CM, Walker AR, Anazodo AC, Hacker NF, Chapman M, Opdahl S, Jorm L, Norman RJ, Stern C, Sansom-Daly UM, Chambers GM, Venetis C.   +11 more
europepmc   +1 more source

Long-Term Colorectal Cancer Incidence After Adenoma and Serrated Polyp Removal: Results From the Colonprev Trial. [PDF]

United European Gastroenterol J
Cubiella J, García-Benito C, Castells A, Quintero E, Bujanda L, Castán-Cameo S, Díaz-Tasende J, Lanas Á, Ono A, Frías-Arrocha E, Hernández C, Jover R, Andreu M, Carballo F, Morillas JD, Salas D, Regueiro-Expósito C, Davila-Piñón P, Diez-Martín A, COLONPREV study investigators.   +19 more
europepmc   +1 more source