Results 131 to 140 of about 544,628 (264)

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Understanding Barriers to Cancer Pain Management: Insights From Patients and Healthcare Professionals-A Systematic Review. [PDF]

Public Health Chall
Admassie BM, Endeshaw AS, Belete KG, Teshome D, Demilew BC, Getahun AB, Molla MT, Alemayehu TY, Boled AT, Alemnew EF, Diress GM, Admass BA.   +11 more
europepmc   +1 more source

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

Advanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino, Phuoc Thien Phan, James Davies, Bibhu Sharma, Tianruo Guo, Chi Cong Nguyen, Nigel H. Lovell, Thanh Nho Do   +7 more
wiley   +1 more source

Linking Cancer Pain Features and Biosignals for Automatic Pain Assessment. [PDF]

Cancers (Basel)
Cascella M, Perri F, Ottaiano A, Santorsola M, Marciano ML, Rampetta FR, Pontone M, Crispo A, Sabbatino F, Franci G, Esposito W, Cisale G, Romano M, Amato F, Scuotto A, Santoriello V, Ponsiglione AM.   +16 more
europepmc   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Pharmacological Mechanisms and Clinical Applications of Oxycodone in Cancer Pain Management: A Narrative Review. [PDF]

Drug Des Devel Ther
Xia Y, Huang G.
europepmc   +1 more source

Adult Cancer Pain [PDF]

Journal of the National Comprehensive Cancer Network, 2010
Robert, Swarm, Amy Pickar, Abernethy, Doralina L, Anghelescu, Costantino, Benedetti, Craig D, Blinderman, Barry, Boston, Charles, Cleeland, Nessa, Coyle, Oscar A, Deleon-Casasola, June G, Eilers, Betty, Ferrell, Nora A, Janjan, Sloan Beth, Karver, Michael H, Levy, Maureen, Lynch, Natalie, Moryl, Barbara A, Murphy, Suzanne A, Nesbit, Linda, Oakes, Eugenie A, Obbens, Judith A, Paice, Michael W, Rabow, Karen L, Syrjala, Susan, Urba, Sharon M, Weinstein   +24 more
openaire   +2 more sources

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Advances in the Pathophysiology and Management of Cancer Pain: A Scoping Review. [PDF]

Cancers (Basel)
Varrassi G, Paladini A, Tran YV, Pham VP, Al Alwany AA, Farì G, Caruso A, Mercieri M, Pergolizzi JV, Kaye AD, Breve F, Corriero A, Gharibo C, Leoni MLG.   +13 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source