Results 251 to 260 of about 590,849 (312)

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source

Post-mastectomy pain syndrome as a model for mixed pain: clinical evidence from a specialized cancer pain clinic. [PDF]

Front Med (Lausanne)
Khashan M, Brill S, Hochberg Y, Hochberg U.   +3 more
europepmc   +1 more source

Long Noncoding RNA H19 Mediates STAT3‐Dependent Activation of Keratinocytes and Fibroblasts in Systemic Sclerosis Skin

Arthritis &Rheumatology, EarlyView.
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz, Christopher W. Wasson, Rebecca L. Ross, Francesco Del Galdo   +3 more
wiley   +1 more source

Evaluating buprenorphine to treat cancer pain: a systematic review protocol. [PDF]

Syst Rev
Khateeb R, Powell V, Rosenberg J, Rose L, Sheehan K, Mackey C, Papaioannou P, Silveira M.   +7 more
europepmc   +1 more source

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

Arthritis &Rheumatology, EarlyView.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu, Zhu Yan, Xueting Peng, Meixuan Li, Juan Wang, Yan Zhang, Xiaoqian Hu, Mingzhu Zhou, Kaixuan Ren, Dan Zhang, Xingyi Guo, Yumin Xia, Huanhuan Huo   +12 more
wiley   +1 more source

The 3P-CP model: Expanding our conceptualization of cancer pain. [PDF]

Cancer
Azizoddin DR, Zhao J, Somers TJ, Taylor SE, Winger JG, Dorsey SG, Orris S, Nasta A, Schenker Y, Merlin JS, Jim HSL, Schreiber KL, Bulls HW.   +12 more
europepmc   +1 more source

Association of a standardized painless ward model with cancer pain control and hospitalization outcomes: a retrospective cohort study. [PDF]

Support Care Cancer
Chen H, Yang L, He Y, Liang X, Liu Y, Huang Y.   +5 more
europepmc   +1 more source

Combined spinal cord stimulation and intrathecal Morphine-Sufentanil therapy for refractory cancer pain: a case report. [PDF]

Front Aging
Zhang ZS, Zhang Y, Wu J.
europepmc   +1 more source

Targeting Neuropilin-1 for Cancer Pain Treatment: A Trial With Potential for Clinical Translation. [PDF]

Cancer Control
Shen S, Lin A, Lan C, Xia Z, Yu M, Qiang N, Ao J, Chen G.   +7 more
europepmc   +1 more source