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A systematic review undertaken to map the current landscape of locoregional de-escalation trials to inform future research. Online databases and trial registries were searched to identify ongoing, recently completed or published studies de-escalating ...
Alan D. McCrorie +4 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Exploring colorectal cancer patients' perceptions of the quality of their care [PDF]
This report discusses the local situation in Halton with regard to colorectal cancer care by exploring how patients perceived the quality of their care.Widnes Primary Care ...
Perry, Catherine +2 more
core +2 more sources
Awareness of genomic testing among patients with breast cancer in Europe
Purpose: Genomic testing, involving expression profiling of tumour tissue, is a powerful tool for determining appropriate treatments for certain cancer patients.
Antonella Cardone +11 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Cancer Trends: Cervical cancer
In the period 2013-2015, invasive cancer of the cervix uteri (ICD10: C53) accounted for just over 1% of all invasive cancers (excluding non-melanoma skin cancer) in Ireland, with an average of 262 cases diagnosed per year.
National Cancer Registry Ireland (NCRI)
core
Treatment Outcome of Cervical Cancer Patients at Ocean Road Cancer Institute, Dar es salaam [PDF]
Cervical cancer is the second commonest malignancy in females globally. Cancer of the cervix has a devastating impact on women’s health in developing countries especially Africa since more than 75% of the worldwide burden of the disease occurs in these ...
Majinge, Peter MC
core
Risk factors for delay in symptomatic presentation: a survey of cancer patients [PDF]
Background: Delay in symptomatic presentation leading to advanced stage at diagnosis may contribute to poor cancer survival. To inform public health approaches to promoting early symptomatic presentation, we aimed to identify risk factors for delay in ...
F Warburton +10 more
core +2 more sources
Effective antibiotics are a cornerstone of treatment for heavily immunocompromised patients such as those undergoing cancer treatment or transplantation procedures, as these patients are at particularly high risk of adverse outcomes from infections ...
Matteo Bassetti +14 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

