Results 121 to 130 of about 766,086 (315)

Dietary Agents in Prevention of Prostate Cancer

, 2008
Prostate cancer is the second leading cause of internal malignancy among men worldwide, with an annual incidence of 679,000 cases, and an annual mortality load of 220,000 deaths, making it the sixth leading cause of cancer mortality among men.
Sural, Yavuz Selim, Turgay, Aye San, Turan, Dilek, Sari, Dilek   +3 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Making a difference for Northern Territory Women : six years on : NT women's cancer prevention program report to June 1999

, 2001
This report 'Making A Difference For Northern Territory Women-Women's Cancer Screening' shows the rewarding work of the first six years of the Women's Cancer Prevention Program (WCPP) of Territory Health Services (THS).
Women's Cancer Prevention Program
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Grand challenges in global health and the practical prevention program? Asian focus on cancer prevention in females of the developing world

, 2003
In response to the request for 'Breakthrough Questions' for 'Grand Challenges in Global Health' recently published in Nature, the Asian Pacific Organization for Cancer Prevention should focus its attention on what projects are of the highest priority for
Moore M.A., Mosavi-Jarrahi A., Basu P.S., Qiao Y.-L., Yoo K.-Y., Srivatanakul P., Chen K., Aydemir G., Anh P.H., Sriamporn S., Tajima K., Tsuda H., Gajalakshmi V., Shin H.R., Ngoan L.T., Bhurgri Y., Tokudome S., Hirose K.   +17 more
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CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Antioxidants May Protect Cancer Cells from Apoptosis Signals and Enhance Cell Viability

, 2013
Quercetin is one of the most abundant dietary flavonoids widely present in many fruits and vegetables. Previous in vitro studies has shown that quercetin acts as an antioxidant and anti-inflammatory agent and it has potent anticarcinogenic properties as ...

core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Skin cancer prevention and education initiative, 2008/2009 : from the Division of Cancer Prevention and Control

The Centers for Disease Control and Prevention (CDC) provides leadership for nationwide efforts to reduce illness and death caused by skin cancer, which is likely the most common form of cancer in the United States.

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Perceptions and opinions towards skin cancer prevention in Malaysia : a qualitative approach

, 2011
Introduction: Malignant melanoma in particular is one of the few remaining cancers with an increasing incidence. Objectives: The objective of this study is to explore the perceptions and opinions of young Malaysians towards skin cancer prevention ...
Al-Naggar, Thekra H., Al-Naggar, Redhwan A., Bobryshev, Yuri V. (R17559)   +2 more
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