Results 251 to 260 of about 766,086 (315)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Efficacy of Helicobacter pylori Eradication for Gastric Cancer Prevention in Older Adults. [PDF]

Korean J Helicobacter Up Gastrointest Res
Lee J.
europepmc   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Expanding Cancer Prevention: Strategies Integrated into Occupational Health Surveillance. [PDF]

Cancers (Basel)
Collatuzzo G, Godono A, Fiorini G, Vencovsky D, Giordani S, Biagioli V, Pinto-Vidal FA, Seyyedsalehi MS, Kostrzewa M, Honrado A, Bruno D, Tardon A, Mates D, Schneider-Kamp A, Fabianova E, Boffetta P.   +15 more
europepmc   +1 more source

The meat processing exposome in Africa: integrating traditional culinary practices, environmental co-exposures, and cancer prevention strategies. [PDF]

Front Oncol
Ndebia EJ, Kamsu GT.
europepmc   +1 more source

Are gynecologists prepared to offer anal cancer prevention services?: a qualitative study of barriers to implementation in the United States. [PDF]

Prev Med Rep
Gaydos LM, Buchanan MNV, Conageski C, Sabben G, Jeudin P, Flowers L.   +5 more
europepmc   +1 more source

Physical activity interventions for Asian Americans in cancer prevention and control: a scoping review. [PDF]

Cancer Causes Control
Sheng J, Wang H, Hitchcock M.
europepmc   +1 more source

Social Determinants of Health and Cancer Prevention Guideline Behaviors.

JAMA Netw Open
Chiang KE, Padilla HM, Callands TA, Muilenburg JL, Chantaprasopsuk S, Bates-Fraser LC, Elahy V, Patel AV, Rees-Punia E.   +8 more
europepmc   +1 more source