Results 71 to 80 of about 668,742 (269)

Suicide risk transition and cumulative incidence post-cancer diagnosis: retrospective cohort study utilizing population-based cancer registry in Japan

BMC Cancer
Background Suicide risk in cancer patients peaks early post-diagnosis; however, detailed studies on its changes are scarce. We analyzed population-based cancer registry data to identify trends in suicide risk and incidence following diagnosis among ...
Kaname Watanabe, Sho Nakamura, Choy-Lye Chei, Hiroto Narimatsu   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Corrigendum: Construction and Validation of a Lung Cancer Risk Prediction Model for Non-Smokers in China

Frontiers in Oncology, 2022
Lan-Wei Guo, Zhang-Yan Lyu, Qing-Cheng Meng, Li-Yang Zheng, Qiong Chen, Yin Liu, Hui-Fang Xu, Rui-Hua Kang, Lu-Yao Zhang, Xiao-Qin Cao, Shu-Zheng Liu, Xi-Bin Sun, Jian-Gong Zhang, Shao-Kai Zhang   +13 more
doaj   +1 more source

Lifetime risk of developing and dying from cancer in Henan Province, China: current status, temporal trends, and disparities

Journal of the National Cancer Center
Objective: To understand the current status and changing trends in the lifetime risk of residents in Henan Province, China to develop and die from cancer.
Qiong Chen, Shuzheng Liu, Yin Liu, Hongwei Liu, Hong Wang, Lanwei Guo, Huifang Xu, Xiaoli Guo, Xiaoyang Wang, Ruihua Kang, Liyang Zheng, Shaokai Zhang   +11 more
doaj   +1 more source

The Korean National Codes Against Cancer: background of their establishment and the revision process [PDF]

Epidemiology and Health
The Korean National Codes Against Cancer provide guidelines for cancer prevention. The inaugural edition was published in 2006, followed by a major revision in 2016.
Yoonjoo Choi, Jin-Kyoung Oh, Ayoung Byeon, Byungmi Kim   +3 more
doaj   +1 more source

Nutrition and Cancer Prevention

International Journal of Immunopathology and Pharmacology, 2012
Cancer cells invade surrounding tissues and metastasize to distant sites. Diet high in fat is a strong link to, and perhaps causes, a high incidence of tumours. Trans-fatty acid might impair the function and it could be involved in the development of cancer. Cholesterol is also strongly suspected to be involved in the development of tumours, therefore
TETE', Stefano, NICOLETTI, Mauro, Saggini A, Maccauro G, Rosati M, CONTI, FIORELLA, CIANCHETTI, Ettore, TRIPODI, Domenico, TONIATO, ELENA, FULCHERI, Mario, SALINI, VINCENZO, Caraffa A, Antinolfi P, Frydas S, Pandolfi F, CONTI, Pio, Potalivo G, Theoharides TC   +17 more
openaire   +5 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Global prevalence and ethnic variation of pathogenic BRCA1/2 variants in breast cancer: a systematic review and meta-analysis

Journal of Translational Medicine
Background The breast cancer (BC) susceptibility genes 1 (BRCA1) and BC susceptibility genes 2 (BRCA2) are critical genes associated with hereditary breast cancer, and their mutation prevalence might greatly vary across different ethnic populations. This
Najeeb Ullah Khan, Huijun Lei, Jinzhen Fu, Ruijiao Lei, Xukai Chen, Sana S. Alqarni, Tianhui Chen   +6 more
doaj   +1 more source