Results 121 to 130 of about 3,898,138 (262)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Contralateral breast cancer after radiotherapy and hormone therapy in two cohorts of US breast cancer survivors [PDF]

BACKGROUND: Radiotherapy increases contralateral breast cancer risk, while hormone therapy reduces it; their combined effects are unclear. METHODS: Data from two US retrospective cohort studies of 5-year breast cancer survivors (stage I-III, ages 20-84),
Smith, Susan A., Ramin, Cody, Howell, RM, Buist, Diana S. M., Saha, M, Vo, Jacqueline B., Weinmann, Sheila, Veiga, Lene H. S., Curtis, RE, Weinmann, S, Lee, C, Bodelon, C, Aiello Bowles, EJ, Feigelson, HS, Berrington de Gonzalez, Amy, Smith, SA, Ramin, C, Feigelson, Heather Spencer, Howell, Rebecca M., Gierach, GL, Bodelon, Clara, Aiello Bowles, Erin J., Mille, Matthew M., Veiga, LHS, Curtis, Rochelle E., Vo, JB, Saha, Monjoy, Gierach, Gretchen L., Lee, Choonsik, Buist, DSM, Mille, MM, Berrington de Gonzalez, A   +31 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Patient-reported outcome and prognostic factors for survival in patients with metastases in soft tissue treated with palliative radiotherapy

Technical Innovations & Patient Support in Radiation Oncology
Purpose: To determine the overall result of treatment with palliative radiotherapy for patients with soft tissue metastases and to identify prognostic factors for overall survival. Methods and materials: From September 2015 until April 2023, 120 patients
Lijanne Otto-Vollaard, Marcella Cramer, Erik van Werkhoven, Ingrid Lokken, Ilse M.N. de Pree, Joost J. Nuyttens   +5 more
doaj   +1 more source

Radiotherapy for Cancer [PDF]

BMJ, 1939
openaire   +2 more sources

Patterns of fatigue related to advanced disease and radiotherapy in patients with cancer-a comparative cross-sectional study of fatigue intensity and characteristics

, 2009
Goals of work This cross-sectional comparative study was designed to explore and describe the prevalence and patterns of cancer-related fatigue in patients with advanced cancer as well as patients undergoing curative radiotherapy.
Furst, Carl Johan, Lundh Hagelin, Carina, Wengström, Yvonne,, Fürst, Carl Johan,, Wengstrom, Yvonne, Lundh Hagelin, Carina,, Hagelin, Carina Lundh,, Hagelin, CL, Furst, CJ, Wengstrom, Y   +9 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Radiotherapy and Cancer [PDF]

Postgraduate Medical Journal, 1946
openaire   +3 more sources

Radiotherapy of Oligometastatic Cancers

Cancers
The enhanced multidisciplinary treatment approach and the widespread use of advanced imaging techniques have led to an improvement in survival rates, inevitably associated with an increase in the number of oligometastatic diagnoses in cancer patients [...]
Filippo Alongi, Simona Gaito
openaire   +2 more sources

Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial

, 2014
If treatment of the axilla is indicated in patients with breast cancer who have a positive sentinel node, axillary lymph node dissection is the present standard.
Bouma, Willem H., Rutgers, Emiel J. T., Veltkamp, Sanne C, de Graaf, Peter W, Marinelli, Andreas, Mansel, Robert E, Bouma, Willem H, Bogaerts, Jan, Slaets, Leen, Duez, Nicole J, van de Velde, Cornelis J. H., Orzalesi, Lorenzo, Merkus, Jos W S, Messina, Carlo G M, Westenberg, A. Helen, Nieuwenhuijzen, Grard A. P., van der Mijle, Huub C. J., Straver, Marieke E., de Graaf, Peter W., Schinagl, Dominic A X, Rutgers, Emiel J T, Mansel, Robert E., Merkus, Jos W. S., Klinkenbijl, Jean H G, van der Mijle, Huub C J, Donker, Mila, Belkacemi, Yazid, Westenberg, A Helen, Straver, Marieke E, Snoj, Marko, Bundred, Nigel J., Schinagl, Dominic A. X., Meijnen, Philip, Duez, Nicole J., van de Velde, Cornelis J H, van Dalen, Thijs, Petignat, Patrick, Coens, Corneel, Nieuwenhuijzen, Grard A P, Messina, Carlo G. M., Cataliotti, Luigi, van Tienhoven, Geertjan, Klinkenbijl, Jean H. G., Veltkamp, Sanne C., Bundred, Nigel J, Rijna, Herman   +45 more
core   +1 more source