Results 71 to 80 of about 3,898,138 (262)

Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation [PDF]

, 2017
In prostate cancer, androgen deprivation therapy (ADT) enhances the cytotoxic effects of radiotherapy. This effect is associated with weakening of the DNA damage response (DDR) normally supported by the androgen receptor.
Liu, Zhao, Sentai Ding, Neil B. Desai, Hutchinson, Ryan, Dehm, SM, Ding, Sentai, Xiangyi Li, Xing, C, Jeffrey Li, Desai, NB, Ding, S, Xu, K, Kangling Xu, Rui Li, de Bono, Johann S, Ramanand, SG, Liu, Xihui, Gao, Y, Mohammed S. Kanchwala, Scott M. Dehm, Mani, RS, Ryan Hutchinson, Ganesh V. Raj, Desai, Neil B, Woldu, Solomon L, Gao, Yunpeng, Zhao Liu, Burma, S, Yin, Yi, Kanchwala, MS, Yin, Y, Li, Xiangyi, Liu, X, Liu, Z, Feng, FY, Xihui Liu, Li, J, Kanchwala, Mohammed S, Hutchinson, R, de Bono, JS, Baek, G, Mani, Ram S, Benjamin P.C. Chen, Solomon L. Woldu, Burma, Sandeep, Ramanand, Susmita G, Ding, Sam, Chen, Benjamin PC, Xing, Chao, Li, Jeffrey, Feng, Felix Y, Susmita G. Ramanand, Johann S. de Bono, Chao Xing, Baek, GuemHee, Dehm, Scott M, Raj, GV, Felix Y. Feng, Yunpeng Gao, Li, Rui, Yi Yin, Li, X, Raj, Ganesh V, Chen, BPC, Sandeep Burma, Ram S. Mani, Xu, Kangling, Woldu, SL, GuemHee Baek, Sam Ding, Li, R   +70 more
core   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

Influence of Different Radio-chemotherapy Modes for Incidence of Radiation Pneumonitis in Patients with Lung Cancer

Zhongliu Fangzhi Yanjiu, 2018
Objective To compare the difference of different radio-chemotherapy modes and clinical characters for more than grade 2 radiation pneumonitis (RP) incidence in patients with lung cancer.
LIU Ruifeng, WEI Shihong, ZHANG Qiuning, LUO Hongtao, DONG Yumei, WANG Xiaohu   +5 more
doaj   +1 more source

Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models.

, 2020
Physical and chemical DNA-damaging agents are used widely in the treatment of cancer. Double-strand break (DSB) lesions in DNA are the most deleterious form of damage and, if left unrepaired, can effectively kill cancer cells.
Dahmen, H, Vassilev, LT, Zenke, FT, Wilm, C, Fuchss, T, Blaukat, A, Kirkin, V, Zimmermann, A, Amendt, C, Grombacher, T, Sirrenberg, C, Pehl, U   +11 more
core   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Effect of Whole-course Nutrition Support on Nutritional Status of Patients with Locally Advanced Nasopharyngeal Carcinoma

Zhongliu Fangzhi Yanjiu, 2020
Objective To investigate the effect of whole-course nutrition support on nutritional status of patients with locally advanced nasopharyngeal carcinoma (NPC).
WEI Xueyan, HAN Guang, LI Ying, HU Desheng   +3 more
doaj   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Phase II trial on SBRT for unresectable liver metastases: long-term outcome and prognostic factors of survival after 5 years of follow-up

Radiation Oncology, 2018
Background The aim of this study was to evaluate long-term efficacy and survival prognostic factors of stereotactic body radiation therapy (SBRT) for un-resectable liver metastases in patients enrolled in a prospective phase II trial.
Marta Scorsetti, Tiziana Comito, Elena Clerici, Ciro Franzese, Angelo Tozzi, Cristina Iftode, Lucia Di Brina, Pierina Navarria, Pietro Mancosu, Giacomo Reggiori, Antonella Fogliata, Stefano Tomatis, Guido Torzilli, Luca Cozzi   +13 more
doaj   +1 more source

Inhibition of Delta-like Ligand 4 enhances the radiosensitivity and inhibits migration in cervical cancer via the reversion of epithelial–mesenchymal transition

Cancer Cell International, 2020
Background Concurrent chemoradiotherapy is the common first-line treatment for patients with advanced cervical cancer. However, radioresistance remains a major clinical challenge, which results in recurrence and poor survival. Many studies have shown the
Shan-Shan Yang, De-Yang Yu, Yu-Ting Du, Le Wang, Lina Gu, Yun-Yan Zhang, Min Xiao   +6 more
doaj   +1 more source

The role of AIMP3, a putative tumour suppressor gene, as a predictive biomarker of response to chemo/radiotherapy in vitro and in patients with muscle-invasive bladder cancer. [PDF]

, 2015
Bladder cancer is the second most common urological cancer after prostate cancer and is one of the leading causes of cancer mortality in most western countries.
Gurung, PMS
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