Results 111 to 120 of about 5,278,927 (357)
Ronja Thallner,1 Christoph Gumbinger,1 Anja Hohmann,1 Antje Wick,1 Wolfgang Wick,1 Loraine Busetto1,2 1Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany; 2Institute for Medical Virology, Goethe University Frankfurt, University ...
Thallner R +5 more
doaj
Last Year\u27s Virus, This Year\u27s Cancer Treatment [PDF]
For hundreds of years, cancer has stumped medical professionals across the world as a cure evaded them. Now, a new approach to battling cancer has entered the arena: viruses.
Collins, Olivia
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
There is an urgent need for solutions to the economic and social inequalities in cancer care that still exist in many European countries. Patient preferences, ‘big data’, mobile digital technology and molecular and genomic profiling are among the ...
Francesco deLorenzo, Kathi Apostolidis
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Trypanosoma cruzi, cancer and the Cold War Trypanosoma cruzi, câncer e a Guerra Fria
In the summer of 1946, the international community of cancer researchers was inspired by the announcement that two Soviet scientists, Nina Kliueva and Grigorii Roskin, had discovered anticancer properties in culture extracts made from the South American ...
Nikolai Krementsov
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Cancer on the Margins: Method and Meaning in Participatory Research [PDF]
Emily S. Kolker
openalex +1 more source

