Addressing cancer care in low- to middle-income countries: a call for sustainable innovations and impactful research [PDF]
Daniela Cristina Stefan, Shenglan Tang
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This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
2020 Young Researcher Forum for 9th European Congress on Breast Cancer, Women's Health and Therapeutics [PDF]
brahim Mashaal
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Research Progress of Antibody-drug Conjugates in Advanced Non-small Cell Lung Cancer
CHEN Yarui +4 more
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This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
From the Catastrophic Objective Irreproducibility of Cancer Research and Unavoidable Failures of Molecular Targeted Therapies to the Sparkling Hope of Supramolecular Targeted Strategies [PDF]
И. В. Алексеенко +3 more
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Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
International symposium on emerging perspectives in clinical cancer research: meeting report
K. S. Z�nker, Enrico Mihich
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Head and Neck Cancer Clinical Research on ClinicalTrials.gov: An Opportunity for Radiation Oncologists [PDF]
Vinayak Muralidhar +6 more
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Gastrointestinal/genitourinary perforation and fistula formation with or without bevacizumab in patients with previously irradiated recurrent cervical cancer: a Korean multicenter retrospective study of the Gynecologic Oncology Research Investigators Collaboration (GORILLA) group (GORILLA-1001) [PDF]
Woo Yeon Hwang +12 more
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