Results 181 to 190 of about 5,208,219 (312)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Breast cancer: When do you stop reading the literature?

South African Journal of Science, 2016
Brenda Wingfield
doaj   +1 more source

Informatics at the Frontier of Cancer Research. [PDF]

Cancer Res
Noller K, Botsis T, Camara PG, Ciotti L, Cooper LAD, Goecks J, Griffith M, Haas BJ, Ideker T, Karchin R, Kontos D, Lai J, Marcus D, Meyer CA, Naegle K, Pati S, Peters B, Pratt D, Raphael BJ, Reich M, Savova GK, Wright C, Fertig EJ, Bakas S.   +23 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

ISG20: The multifaceted 'molecular star' in cancer research (Review). [PDF]

Oncol Rep
Zhu X, Jiang S, Zhang L, Zou S, Zhang H, Zhang J, Chen L, Li H, Zong Z.   +8 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

The impact of focused federal initiatives on pediatric cancer research. [PDF]

Cancer
Jagu S, Smith MA, Seibel NL, Tonorezos ES, Widemann BC, Gibbons HA, Holohan MK, Ababiya ZA, Guidry Auvil JM, Lowy DR, Doroshow JH, Lubenow AE, Reaman GH.   +12 more
europepmc   +1 more source

Enhancing cancer registry data for comparative effectiveness research (CER) project: overview and methodology.

, 2014
Vivien W. Chen, Christie R. Eheman, Christopher J. Johnson, Monique N. Hernandez, David Rousseau, Timothy Styles, Dee W. West, Mei‐Chin Hsieh, Anne M. Hakenewerth, Maria O. Celaya, Randi Rycroft, Jennifer M. Wike, Melissa J. Pearson, Judy Brockhouse, Linda Mulvihill, Kevin B. Zhang   +15 more
openalex   +1 more source

Reports of Successful Research Activities: Cancer and Cancer Chemotherapy [PDF]

, 1965
Korst, Donald R.
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source