Results 201 to 210 of about 24,047,971 (353)

Proceedings of the American Association for Cancer Research: Twenty-Eighth Annual Meeting: New York, April 17, 1935

, 1936

openalex   +1 more source

Problems in Cancer Research [PDF]

, 1963
F. J. C. Roe
openalex   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Prostate Cancer-Research Advances in Early Detection. [PDF]

J Clin Med
Czerw A, Deptała A, Głowacka M, Partyka O, Pajewska M, Czerw N, Badowska-Kozakiewicz A, Sygit K, Kopczyński Z, Czarnywojtek P, Gąska I, Kaczmarski M, Banaś T, Grochans E, Grochans S, Cybulska AM, Schneider-Matyka D, Bandurska E, Ciećko W, Dykowska G, Sienkiewicz Z, Drobnik J, Pobrotyn P, Grata-Borkowska U, Furtak-Pobrotyn J, Sierocka A, Marczak M, Pokorna-Kalwak D, Kozlowski R.   +28 more
europepmc   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Adherence to World Cancer Research Fund/American Institute for Cancer Research Guidelines and Mortality Among Participants with Colorectal Cancer in the MEC Cohort. [PDF]

Cancer Epidemiol Biomarkers Prev
Asiimwe E, Tolstykh I, Chan JM, Kenfield SA, Wilkens LR, Park SY, Le Marchand L, Huang BZ, Haiman CA, Cheng I, Van Blarigan EL.   +10 more
europepmc   +1 more source

The Origin and Early History of the Institute of Cancer Research of the Royal Cancer Hospital [PDF]

, 1965
DennisA. Brunning, C E Dukes
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Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Organoid technology in cervical cancer research. [PDF]

Am J Cancer Res
Ye H, Song L, Li Q, Shen C, He Y, Li L.
europepmc   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source