Results 221 to 230 of about 5,278,927 (357)

Organoids in Cancer Research and Regenerative Medicine: Current Status, Challenges, and Future Prospects. [PDF]

MedComm (2020)
Li R, Wu Y, Zheng Z, Zhou F, Xu K, Su J.
europepmc   +1 more source

Research Progress on Natural Products Overcoming EGFR-TKIs Resistance in Non-Small Cell Lung Cancer

起凤 宋
openalex   +1 more source

Bridging the Gap: Embedding Psychosocial Oncology Research into Comprehensive Cancer Care for Children and Young People [PDF]

Ursula M. Sansom‐Daly, Jordana K. McLoone, Joanna E. Fardell, Holly E. Evans, Brittany C. McGill, Eden G. Robertson, Christina Signorelli, Sarah J. Ellis, Lauren Ha, Kate Hetherington, Rachel Houweling, Suzanne M. Nevin, Clarissa E. Schilstra, Richard Mitchell, Michelle Haber, Richard J. Cohn, Claire E. Wakefield   +16 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A global bibliometric perspective on autophagy and tumor microenvironment in cancer research. [PDF]

Discov Oncol
Debnath I, Kundu M.
europepmc   +1 more source

Scoping Review of Colorectal Cancer Research in Libya: Gaps and Opportunities in Peer-Reviewed Publications

Abeir El Mogassabi, Lugien Elshakmak, Nadin Omer Hassan, Enas Mohamed Salem, Khalil Tamoos   +4 more
openalex   +1 more source

Cancer care coordination: opportunities for healthcare delivery research [PDF]

, 2018
Sallie J. Weaver, Paul B. Jacobsen
openalex   +1 more source

Institute of Cancer Research [PDF]

, 2008

core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Cancer research and the mainstream of biology. [PDF]

Front Cell Dev Biol
Maimets T.
europepmc   +1 more source