Results 231 to 240 of about 5,278,927 (357)

An overview of the use of artificial neural networks in lung cancer research [PDF]

open access: hybrid, 2017
Luca Bertolaccini   +3 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Beyond Rodents: Alternative Animal Models in Colorectal Cancer Research. [PDF]

open access: yesInt J Mol Sci
Xiong W   +8 more
europepmc   +1 more source

CRISPR-Cas9: a promising genetic engineering approach in cancer research [PDF]

open access: gold, 2018
Zubair Ahmed Ratan   +8 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

CYberinfrastructure for COmparative effectiveness REsearch (CYCORE): improving data from cancer clinical trials [PDF]

open access: hybrid, 2010
Kevin Patrick   +13 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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