Results 241 to 250 of about 2,995,797 (334)

Evidence of Epigenetic Oncogenesis: A Turning Point in Cancer Research. [PDF]

Bioessays
Capp JP, Aliaga B, Pancaldi V.
europepmc   +1 more source

The Acid Number of the Lipids on the Intact and the Stripped Skin Surface in Psoriatics*†*From the Department of Dermatology and Syphilology, New York University Post-Graduate Medical School (Dr. Marion B. Sulzberger, Chairman) and the Skin and Cancer Unit of University Hospital, New York 3, N.Y.†This investigation was supported by Grant DA-49-007-MD-753 from the Research and Development Division, Department of the U.S. Army.

, 1960
Frank Herrmann, Richard K. Scher, William M. Coon, Leona Mandol   +3 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Microfluidic Applications in Prostate Cancer Research. [PDF]

Micromachines (Basel)
Szewczyk K, Jiang L, Khawaja H, Miranti CK, Zohar Y.   +4 more
europepmc   +1 more source

Influence of Hair Growth Cycle on Melanocyte Activation in Rabbit Skin After a Single Application of Methylcholanthrene11From the Biological Station, Roswell Park Memorial Institute, Springville, New York. Presented, in part, at the Annual meeting of The American Association for Cancer Research, April 8–10, 1960, Chicago, Illinois.

, 1961
Walter C. Quevedo, J. E. Isherwood
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Network pharmacology and AI in cancer research uncovering biomarkers and therapeutic targets for RALGDS mutations. [PDF]

Sci Rep
Zaidh SM, Vengateswaran HT, Habeeb M, Aher KB, Bhavar GB, Irfan N, Lakshmi KNVC.   +6 more
europepmc   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source