Results 81 to 90 of about 4,254,676 (261)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2019 This review showed that there has not been a lot of research in this area previously. Most of the research looked at the more common cancers in Ireland, such as prostate, colorectal, and breast.
Donnelly, Conan +5 more
core
Survivors Voices: Survivors Views on Restorative Justice
, 2021 Choice, agency and control are taken away from survivors of sexual and domestic abuse everyday by those who cause them harm. So, what happens when people who are in positions of care, who provide support services decide that something is not suitable for
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Current OncologyThe study aims to investigate the Health-Related Quality of Life (HRQOL) in lung cancer survivors, comparing it with the HRQOL of survivors of other types of cancer, analyzing its association with clinically significant distress, and exploring the ...
Yolanda Andreu +5 more
doaj +1 more source
Living into old age with the consequences of breast cancer [PDF]
, 2013 Purpose of the research: breast cancer survival rates are improving with over 60% likely to live 20 years. As 30% diagnoses occur in women over 70 the prevalence of breast cancer survivors living into older age is increasing.
Foster, Claire L. +13 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Cross-cultural adaptation and validation of the cancer survivors' unmet needs measure among gynecological cancer patients in Indonesia [PDF]
Archive of Oncology, 2020 Background: The number of gynecological cancer survivors in Indonesia is growing, yet little is recognized about their supportive care needs due to a lack of validated assessment to measure them. This study aimed to culturally adapt the Cancer survivors'
Haryani Haryani +6 more
doaj
Online physical activity and sedentary behaviour information for cancer survivors
, 2020 Purpose The purpose of this study is to assess the prevalence, content, and nature of information and/or advice regarding physical activity and sedentary behaviour available online for cancer survivors.
Rowe, Arlen +9 more
core +1 more source