Results 81 to 90 of about 38,308 (260)

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Sexual distress among men with cancer – a cross-sectional study

Acta Oncologica
Background and purpose: Many men with cancer experience that changes created by cancer and its treatment may impair sexual function. However, many studies investigating sexual impairments fail to consider whether such impairments are perceived as ...
Jonas Nahavandipour, Christoffer Johansen, Annamaria Giraldi, Bolette Skjøft Rafn, Annika von Heymann   +4 more
doaj   +1 more source

EXERCISE AND CANCER SURVIVORSHIP

, 2015
Exercise has been identified as an integral component of comprehensive survivorship care and a promising adjuvant therapy to aid in the management of cancer. Leading organisations worldwide now advocate exercise for cancer survivors. Here we briefly review the existing evidence for exercise and survivorship, as well as current research endeavours in ...
Cormie, Prue, Peddle-McIntyre, Carolyn, Hayes, Sandra C., Naumann, Fiona, Turner, Jane, Murnane, Andrew, Baker, Michael K.   +6 more
openaire   +2 more sources

Chronic Respiratory Diseases in the 2023‐Defined WHO Western Pacific Region: Burden and Trends From GBD 2023

Med Research, EarlyView.
Chronic respiratory disease burden in the 2023‐defined WHO Western Pacific Region, 1990–2023: Using the Global Burden of Disease 2023 estimates, this study characterized the incidence, prevalence, deaths, and disability‐adjusted life years (DALYs) associated with chronic respiratory diseases (CRDs) in the 37 WHO Western Pacific Region Member States and
Zhang Yue, Yi‐Cheng Fu, Wen Zuo, Li‐Na Wang, Xing‐Xing Suo, Peng Sun, Jin‐Hui Bian, Ming‐Yan Wang   +7 more
wiley   +1 more source

Prescription patterns demonstrate high demand for treating erectile dysfunction following radical prostatectomy

Acta Oncologica
Background and purpose: Radical prostatectomy can cause erectile dysfunction; however, subsequent treatment with, e.g., phosphodiesterase-5 inhibitors may improve sexual function in the patients.
Signe Benzon Larsen, Annika von Heymann, Hein V. Stroomberg, Anne Sofie Friberg, Klaus Brasso, Andreas Røder, Susanne Oksbjerg Dalton, Randi Karlsen, Pernille Envold Bidstrup, Annamaria Giraldi, Christoffer Johansen   +10 more
doaj   +1 more source

2025 American Thyroid Association Management Guidelines for Adult Patients With Differentiated Thyroid Cancer: What's New for Surgeons?

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract The American Thyroid Association (ATA) has published an update to the 2015 management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer (DTC). This updated version focuses solely on the management of differentiated thyroid cancer, offering a comprehensive set of guidelines for all stakeholders in the care of ...
Chau Nguyen, Amanda Silver Karcioglu, Joseph Scharpf   +2 more
wiley   +1 more source

Enhancing accessibility and impact of digitally enabled clinical trials: the WeShare engagement and equity toolkit

ESMO Real World Data and Digital Oncology
Digital technologies are advancing rapidly, reshaping the way we design, operate, and execute clinical trials. Digitally enabled trials are particularly well-positioned to accelerate the implementation of oncology research by streamlining key clinical ...
M.A. Franzoi, S. Everhard, E. Gillanders, I. Vaz-Luis   +3 more
doaj   +1 more source

Frailty and Recovery Following Free Flap Reconstruction in Head and Neck Cancer: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To review the impact of frailty on various outcomes in geriatric head and neck cancer (HNC) patients undergoing microvascular free flap reconstruction (MFFR). Data Sources MEDLINE, Embase, and World of Science. Review Methods Following PRISMA guidelines, two independent reviewers performed a systematic review of MEDLINE, Embase, and ...
Anvitha R. Metpally, Mitchell T. Victor, Mirian Ramirez, Avinash Mantravadi, Michael W. Sim, Michael G. Moore, Jessica A. Yesensky, Janice L. Farlow   +7 more
wiley   +1 more source

Prophylactic Home‐Based Exercises During Radiotherapy in Head and Neck Cancer: A Randomized Controlled Trial

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective This study investigated the efficacy of a prophylactic, home‐based exercise program administered concomitantly with radiotherapy in patients with head and neck cancer to preserve swallowing function, postural alignment, and cervical range of motion, while assessing lymphedema safety. Study Design Randomized controlled trial.
Burak Erturk, Mehmet Düzlü, Özge P. Erpolat, İlke Keser   +3 more
wiley   +1 more source

BEHAVIORAL AND BIO-PSYCHO-SOCIAL FACTORS IN CANCER SURVIVORSHIP

Journal of Cancer Rehabilitation
The incidence of cancer continues to rise, with over 26 million cancer survivors projected by 2040. As survival rates improve, attention must shift toward comprehensively addressing the needs of cancer survivors, not only including prevention of cancer
Antonino Di Meglio
doaj   +1 more source