Results 311 to 320 of about 334,749 (357)

Cancer Vaccine

, 2011
Akiyama, Shinichiro, Abe, Hiroyuki
openaire   +3 more sources

Tumor Burden Dictates the Neoantigen Features Required to Generate an Effective Cancer Vaccine. [PDF]

Cancer Immunol Res
Garzia I, Nocchi L, Avalle L, Troise F, Leoni G, Seclì L, Antonucci L, Cotugno G, Allocca S, Romano G, Conti L, Caiazza C, Mallardo M, Poli V, Scarselli E, D'Alise AM.   +15 more
europepmc   +1 more source

Synthesis, Antimycobacterial Activity and Computational Insight of novel 1,4‐Benzoxazin‐2‐one Derivatives as Promising Candidates Against Multidrug‐Resistant M. tuberculosis

ChemMedChem, Accepted Article.
To search for new antitubercular agents, we have designed, synthesized, and evaluated a series of 1,4‐benzoxazinone‐based compounds. These molecules showed potent antimycobacterial activity, with MIC between 2 and 8 μg/mL. This interesting profile included activity against several drug‐resistant strains and minimal cytotoxicity against mammalian Vero ...
Daniele Zampieri, Maria Grazia Mamolo, Emanuele Carosati, Diletta Pasin, Alessandro De Logu, Gianluigi Cabiddu, Marko Jukic   +6 more
wiley   +1 more source

Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites

ChemMedChem, EarlyView.
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert, Lucie Paloque, Jean‐Michel Augereau, Flore Nardella, Michel Nguyen, Bernard Meunier, Françoise Benoit‐Vical   +6 more
wiley   +1 more source

Wilms' tumor 1 -targeting cancer vaccine: Recent advancements and future perspectives. [PDF]

Hum Vaccin Immunother
Ogasawara M.
europepmc   +1 more source

Synopsis of the 5th annual Cancer Vaccines and Immunotherapy Colloquium at Walker's Cay

, 2003
Malcolm S. Mitchell, W. Martin Kast
openalex   +2 more sources

Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma [PDF]

, 2019
Artyomov, Maxim N., Bender, Diane, Campian, Jian L., Chicoine, Michael R., Dacey, Ralph G., Dunn, Gavin P., Fritsch, Edward F., Gillanders, William E., Huang, Jiayi, Johanns, Tanner M., Kobayashi, Dale K., Liu, Connor J., Mardis, Elaine R., Miller, Christopher A., Perrin, Richard J., Schreiber, Robert D.   +15 more
core   +1 more source

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium tuberculosis: Progress Toward Novel Antitubercular Agents

ChemMedChem, Accepted Article.
Tuberculosis (TB) is the leading cause of death among infectious diseases, and new studies focusing new anti‐TB drugs are urgent due to the emergence of drug‐resistant strains. In this regard, homoisoflavones, an underexplored subgroup of flavonoids, were explored for their potential as anti‐TB agents.
Sanderson D. Calixto, Juliane S. Falcão, Stella S. Antunes, Marlon H. Araujo, Alexandre L. B. Cunha, David R. Martins, Sarah M. R. Nascimento, Thatiana L. B. V. Simão, Elena B. Lasunskaia, Nelilma C. Romeiro, Paulo R. R. Costa, Michelle Muzitano, Guilherme S. Caleffi   +12 more
wiley   +1 more source

Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes. [PDF]

Bioconjug Chem
Wang AZ, Brink HJ, Bouma RG, Affandi AJ, Nijen Twilhaar MK, Heijnen DAM, van Elk J, Maaskant JJ, Konijn VAL, Stolwijk JGC, Kalay H, Olesek K, van Kooyk Y, van der Schoot JMS, Bentlage AEH, Scheeren FA, Verdoes M, Vidarsson G, Kuijl CP, den Haan JMM.   +19 more
europepmc   +1 more source

Millisecond phase transition kinetics of lyotropic liquid crystalline nanoparticles observed by time‐resolved small angle x‐ray solution scattering

ChemPhysChem, Accepted Article.
This study investigates the dynamic behavior of lyotropic liquid crystal nanoparticles (LCNPs), which are widely recognized for their applications in drug delivery. By employing nanosecond near‐infrared (NIR) laser pulse‐induced temperature jump (T‐jump) and time‐resolved X‐ray solution scattering (TRXSS), the structural dynamics of phase transitions ...
Changmin Lee, Arnold M. Chan, Adam K. Nijhawan, Madeline B. Ho, Irina Kosheleva, Lin X. Chen   +5 more
wiley   +1 more source